Amino acid benefits are simple to name because, without amino acids, we cannot
exist. Every anatomical and physiological feature of a living organism is made
possible through the existence of amino acids.
The nine essential amino acids are histidine, isoleucine, leucine, lysine, methionine,
phenylalanine, threonine, tryptophan, and valine.

Isoleucine is one of three branched-chain amino acids (BCAAs). It helps to increase
the rate of protein synthesis and promotes muscle tissue formation.
Histidine is a precursor to various hormones and metabolites important
to kidney function, gastric secretion, the immune system, and neurotransmission. It
helps to produce red blood cells and hemoglobin.
Lysine has an important part to play in cell division and growth as it is a major
building block of growth factors.
Methionine contains the element sulfur which is essential
to cartilage and liver health and ameliorates hair structure and nail strength. 
Phenylalanine is a precursor of tyrosine hydroxylase, an enzyme that speeds up
catecholamine synthesis and so affects mood.
Threonine increases the uptake of other amino acids such as phenylalanine but also
contributes to neurotransmitter balance in the brain, muscle tissue production, and
immune system function.
Tryptophan is a precursor molecule of niacin (vitamin B3), melatonin and serotonin
and thus essential for sleep and mood.

 Folic acid deficiency
 Chills,
 Fever,
 Flushing (sense of warmth in the face, ears, neck and trunk)

 Increased sweating
 Metabolic disorder
 Vomiting
 Liver damage

Essential amino acids cannot be made by the body. As a result, they must come from
food.
Take extra caution in patients with the following medical conditions:
Severe acidosis
Congestive heart failure

Evening primrose oil has long been used by women to treat hot flashes during menopause.

Evening primrose oil was heavily touted as an effective treatment for eczema

Evening primrose, borage seed, or blackcurrant seed oil provided "moderate" relief of pain and disability in people with rheumatoid arthritis.

Evening primrose oil was first proposed as a possible treatment of diabetic neuropathy

an often debilitating nerve pain mainly affecting the feet and legs.

Evening Primrose Oil is a herbal medicine. Its seeds contain high amount of omega-6 essential fatty acids (EFAs), which have an indirect effect on different glands. This helps to regulate hormones during monthly period and breast feeding. It also helps in reducing pain in the breast.

Major & minor side effects for Evening primrose oil

• upset stomach
• nausea
• diarrhea
• headache

Taking evening primrose oil in limited quantity is safe for pregnant and breastfeeding women. 

It is also safe when applied to the skin.

It should not be taken by patients who have bleeding disorder for increased chance of bruising and bleeding.

There is a concern that taking evening primrose might make seizures more likely in some people.

It should not be used by Schizophrenic patients.

Evening primrose might increase the chance of bleeding during or after surgery.