• Zinc oxide is an inorganic compound with the formula ZnO. ZnO is a white powder that is insoluble in water.
• Zinc (Topical) is a mild antiseptic with skin soothing properties.It works by forming a barrier on the skin to protect it from irritants/moisture

• Zinc oxide topical (for the skin) is used to treat diaper rash, minor burns, severely chapped skin, or other minor skin irritations.
• Zinc oxide rectal suppositories are used to treat itching, burning, irritation, and other rectal discomfort caused by hemorrhoids or painful bowel movement

• Hives
• Itching
• Skin rash
• Worsening of diaper rash
• Burning and stinging of broken skin
• Swelling of the face, lips or tongue.

• If you or your child's symptoms do not improve within 7 days, or if they become worse, check with your doctor.
• If you or your child accidentally swallows the medicine, call the Poison Control Center right away.
• This product may contain inactive ingredients, which can cause allergic reactions or other problems. 

Vitamin B6 is a water-soluble vitamin. Water-soluble vitamins dissolve in water so the body cannot store them.Vitamin B6 is a group of related compounds. It is necessary for maintaining important functions in the body such as glucose and amino acid metabolism, production of RBCs, proper functioning of the nervous system, etc

• Vitamin B6 is used to treat or prevent vitamin B6 deficiency.
• It is also used to treat a certain type of anemia (lack of red blood cells).
• This medicine injection is also used to treat some types of seizure in babies.
• Vitamin B6 (Pyridoxine) provides essential nutrients.
• Vitamin B6 helps the body to:
• Make antibodies. Antibodies are needed to fight many diseases.
• Maintain normal nerve function.
• Make hemoglobin. Hemoglobin carries oxygen in the red blood cells to the tissues. A vitamin B6 deficiency can cause a form of anemia.
• Break down proteins. The more protein you eat, the more vitamin B6 you need.
• Keep blood sugar (glucose) in normal ranges.
• Vitamin B6 is being studied in the prevention of hand-foot syndrome

• Clumsiness
• Numbness of hands or feet
• Unsteady walk
• Sleepiness

• Follow your doctor's instructions about any restrictions on food, beverages, or activity.
• Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
• This medicine is not recommended for use in breastfeeding women unless necessary.

Vitamin B12 is used in the treatment of vitamin B12 deficiency.

Vitamin B12 is a nutrient which the body requires in small amounts to make red blood cells, generate energy, and keep nerve cells healthy.

• Symptoms of Vitamin B12 Deficiency
• Weakness, tiredness, or lightheadedness
• Anemia
• Heart palpitations and shortness of breath
• Pale skin
• A smooth tongue
• Constipation, diarrhea, loss of appetite, or gas 
• Nerve problems like numbness or tingling, muscle weakness, and problems walking
• Vision loss
• Mental problems like depression, memory loss, or behavioral changes 

• Most people can prevent vitamin B12 deficiency by eating enough meat, poultry, seafood, dairy products, and eggs.
• If you don't eat animal products, or you have a medical condition that limits how well your body absorbs nutrients, you can take vitamin B12 in a multivitamin or other supplement and foods fortified with vitamin B12.

This medicine is generally used in a combination with other medicines and supplements to increase their bioavailability.

This medicine is used along with other medicines for the treatment of pulmonary tuberculosis, which is a lung infection caused by the bacteria, Mycobacterium tuberculosis.

Piperine is a naturally occurring alkaloid extracted from black pepper.

Major & minor side effects for Piperine

• Erythematous rash,
• Itching,
• Dry skin,
• Paresthesia (tingling or pricking sensation)

This medicine is not recommended for use in pregnant and breastfeeding women unless necessary.

This medicine may interact with many other medicines including herbs and supplements.

Lycopene being an antioxidant, may stop cancer growth and build up enzymes in the body that help break down cancer-causing agents.as well as its use in the prevention of cardiovascular disease.

Lycopene may help prevent strokes, particularly strokes caused by blood clots.

Lycopene along with other carotenoids may also protect against UV damage caused by the sun.

Lycopene is a natural compound that is found in bright red fruits and vegetables like tomatoes, watermelon, and grapefruit.

Lycopene acts an antioxidant by fighting free radicals in the body. Due to its antioxidant property, it reduces the risk of cancer and cardiovascular disease.

Major & minor side effects for Lycopene prepn

• Nausea
• Diarrhea
• Indigestion
• Vomiting

This medicine is not recommended for use in pregnant and breastfeeding women unless absolutely necessary.

Lycopene may also increase the risk of bleeding when taking certain medications.

Certain supplements like beta-carotene, calcium, and lutein, when taken together with lycopene, may decrease the amount of lycopene absorbed by the gut. 

Chronic, excessive alcohol consumption may also cause a side effect with lycopene.

Levocarnitine is used to treat carnitine deficiency.

Levocarnitine belongs to the class of medications called as amino acid derivative. It works by improving the low levels of carnitine in the body.

Major & minor side effects for Levocarnitine

• Hypersensitivity
• Increased blood pressure
• Increased heartbeat
• Fever
• Seizures

This medicine is considered safe for consumption by pregnant and breastfeeding women.

Caution is advised while administering Levocarnitine to patients with kidney diseases due to the increased risk of adverse effects.

The oral form of this medicine may cause body odor. Appropriate dose adjustments may be done to decrease or stop the body odor.

The oral form of this medicine may cause adverse gastrointestinal symptoms.

• Folic acid is the synthetic form of folate, which is a naturally occurring B vitamin. Folate helps make DNA and other genetic material. It is especially important in prenatal health.
• Folate, also called vitamin B-9, is a B vitamin that naturally occurs in certain foods. Folic acid is the form of folate that manufacturers add to vitamin supplements and fortified foods.

• It helps the body make healthy new red blood cells.
• In its deficiency a person can develop anemia, leading to fatigue, weakness, and a pale complexion.
• It leads to folate deficiency anemia.
• Folate is also important for the synthesis and repair of DNA and other genetic material.
• It is particularly important to get during pregnancy. Folate deficiency during pregnancy can lead to neural tube irregularities, such as spina bifida and anencephaly.
• Folic acid is crucial for early fetal development.
• Neural tube irregularities - Taking folic acid supplements before and during pregnancy will help prevent neural tube irregularities in the fetus.
• It may also reduce the risks of preterm birth, heart irregularities, and cleft palate, among other things.
• Depression - Taking folic acid supplements could make depression medications more effective.
• The Office on Women’s Health recommend that women who are or might become pregnant take 400–800 mcg of folic acid per day, and that people with spina bifida or a family history of neural tube irregularities take 4,000 mcg per day. Those who are breastfeeding should aim to take around 500 mcg per day.
• The body absorbs folic acid from supplements and fortified foods better than the folate from naturally occurring foods.

Skin reactions, seizures, gases problem, diarrhea, irritability, confusion, stomach upset, loss of appetite, and hypersensitivity

It is important to note that folic acid can interact with certain medications.

A person should speak to a doctor before taking folic acid if they have any of the following:

• Epilepsy
• Type 2 diabetes
• Rheumatoid arthritis
• Lupus
• Inflammatory bowel disease (ibd)
• Celiac disease

People undergoing kidney dialysis may also wish to avoid taking folic acid.

Evening primrose oil has long been used by women to treat hot flashes during menopause.

Evening primrose oil was heavily touted as an effective treatment for eczema

Evening primrose, borage seed, or blackcurrant seed oil provided "moderate" relief of pain and disability in people with rheumatoid arthritis.

Evening primrose oil was first proposed as a possible treatment of diabetic neuropathy

an often debilitating nerve pain mainly affecting the feet and legs.

Evening Primrose Oil is a herbal medicine. Its seeds contain high amount of omega-6 essential fatty acids (EFAs), which have an indirect effect on different glands. This helps to regulate hormones during monthly period and breast feeding. It also helps in reducing pain in the breast.

Major & minor side effects for Evening primrose oil

• upset stomach
• nausea
• diarrhea
• headache

Taking evening primrose oil in limited quantity is safe for pregnant and breastfeeding women. 

It is also safe when applied to the skin.

It should not be taken by patients who have bleeding disorder for increased chance of bruising and bleeding.

There is a concern that taking evening primrose might make seizures more likely in some people.

It should not be used by Schizophrenic patients.

Evening primrose might increase the chance of bleeding during or after surgery.

Taking chromium by mouth is effective for preventing chromium deficiency.

Chromium may also be used for improving blood sugar control in people with prediabetes, type 1 and type 2 diabetes, and high blood sugar due to taking steroids and HIV treatments.

Chromium is a mineral. It is called an "essential trace element" because very small amounts of chromium are necessary for human health. There are two forms of chromium: trivalent chromium and hexavalent chromium. The first is found in foods and supplements and is safe for humans. The second is a known toxin that can cause skin problems and lung cancer.

Major &minor side effects for Elemental Chromium

• Acute toxicity,
• Nausea,
• Rash,
• Upset stomach

Chromium is safe to use during pregnancy and breastfeeding.

Chromium is safewhen taken by mouth in amounts that do not exceed the "adequate intake" (AI) levels for children.

Chromium might affect brain chemistry and might make behavioral or psychiatric conditions worse.

Chromium supplements can cause allergic reactions in people with chromate or leather contact allergy. 

Chromium might lower blood sugar levels too much if taken along with diabetes medications.

Biotin is a B complex vitamin used as a nutritional supplementation for dietary shortage or imbalance which may cause hair loss or total alopecia, brittle nails, skin rash in infants, and mild depression.

Biotin is a form of vitamin B that provides essential nutrients.

Major & minor side effects for Biotin

• Hypersensitivity
• Stomach discomfort and pain
• Skin rash

This medicine is considered safe for consumption by pregnant and breastfeeding women.

Use of this medicine in children should be done only under your doctor's supervision.

The effect of therapy with Biotin may occur 3 to 6 months after starting the therapy.

Dialysis patients may require a higher dose due to drug removal during dialysis.

Benfotiamine is a derivative of vitamin B1. Derived from thiamine, this medication is
used as a dietary supplement. It helps to raise tissue and blood levels of thiamine,
which then helps to protect the body from any med conditions arising from low
levels of thiamine such as heart and nerve disorders. It also helps against diabetic
neuropathy.The drug is easily absorbed through cell membranes, thus making it
easier for it to be transported to the cells that most require it.

It is used for the treatment and prevention of vitamin B1 deficiency that cannot be
corrected through dietary modifications. It may also be used for the treatment of
neuropathies and cardiovascular disorders caused due to vitamin B1 deficiency. It
may also be used for the treatment of Beriberi and Wernicke's encephalopathy.

 Cough
 Difficulty in swallowing
 Itching and skin rash
 Swelling of face, lips, eyelids, or tongue
 Difficulty in breathing
 Nausea
 Weight gain
 Burning sensation
 Headache
 Sleepiness

This medicine is not recommended for use in pregnant and breastfeeding women
unless necessary.

This medicine may interact with many other medicines and may cause severe
adverse effects.