ISTAMET D XR 1000 is a fixed-dose combination medication containing Sitagliptin Phosphate (100.00mg/Tablet), Metformin Hydrochloride (1000.00mg/Tablet), and Dapagliflozin (10.00mg/Tablet). This combination is used in the management of type 2 diabetes mellitus. 

• Control of blood sugar levels
• Management of type 2 diabetes mellitus
• Improvement of insulin sensitivity
• Reduction of HbA1c levels

• Vomiting
• Diarrhea
• Nausea
• Hypoglycemia (low blood sugar)
• Increased urination

Take ISTAMET D XR 1000 orally with meals, usually once or twice a day as prescribed by your doctor. Follow the dosage instructions carefully and do not exceed the recommended dose.

• Pregnancy - It is important to consult your doctor before using ISTAMET D XR 1000 during pregnancy as the safety of this combination during pregnancy has not been established.
• Alcohol - Avoid excessive alcohol consumption while taking ISTAMET D XR 1000 as it can increase the risk of lactic acidosis.
• Old Age - No specific precautions are needed for the elderly population. However, dosage adjustments may be necessary based on kidney function.
• Breast Feeding - Consult your doctor before using ISTAMET D XR 1000 while breastfeeding as it is not clear whether the components of this medication pass into breast milk.
• Children - ISTAMET D XR 1000 is not recommended for use in children below a certain age. Consult your doctor for pediatric dosing.

• Store ISTAMET D XR 1000 at room temperature (20-25°C) away from moisture and heat. -
• Keep ISTAMET D XR 1000 out of reach of children. -

• Drug-Drug - Some medications like certain antibiotics, antifungals, or diuretics may interact with ISTAMET D XR 1000. Inform your doctor about all the medications you are taking.
• Drug-Food - Grapefruit and grapefruit juice may interact with ISTAMET D XR 1000. Avoid consuming them while on this medication.
• Drug-Disease - ISTAMET D XR 1000 may need caution in patients with kidney problems or a history of pancreatitis. Inform your doctor about any pre-existing conditions.

• Q. What should I do if I miss a dose of ISTAMET D XR 1000?
  If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
• Q. Can ISTAMET D XR 1000 be used alone or in combination with other diabetes medications?
  ISTAMET D XR 1000 can be used as a standalone treatment or in combination with other diabetes medications under the supervision of a healthcare provider.
• Q. How long does it take for ISTAMET D XR 1000 to start showing its effects?
  The onset of action of ISTAMET D XR 1000 may vary among individuals. It is essential to monitor your blood sugar levels as advised by your doctor to assess the effectiveness of the medication.
• Q. Are there any dietary restrictions while taking ISTAMET D XR 1000?
  Maintaining a healthy diet and following your healthcare provider's dietary recommendations is essential while taking ISTAMET D XR 1000 to help manage your diabetes effectively.
• Q. What are the signs of low blood sugar, and how should I manage it while on ISTAMET D XR 1000?
  Signs of low blood sugar include sweating, shakiness, dizziness, hunger, confusion, and headaches. Always carry a source of sugar (e.g., glucose tablets, fruit juice) to manage hypoglycemia episodes while on ISTAMET D XR 1000.