• Calcium acetate is a natural mineral that works by holding onto phosphate from the diet so that it can pass out of your body.
• Calcium acetate helps reduce phosphate levels in people with advanced kidney disease.
•  People with advanced kidney failure retain phosphate leading to too much phosphate in their bodies (hyperphosphatemia). High   phosphate levels cause hyperparathyroidism, which leads to abnormal bone formation and calcium deposits in tissues.
•  Calcium acetate is a phosphate binder. Calcium acetate, when taken with meals, combines with phosphate in food to form calcium   phosphate, which is poorly absorbed into the body and is excreted in the feces.
•  Binding phosphate in the intestines reduces absorption of phosphate into the body.

•  Calcium acetate is used to prevent high blood phosphate levels in patients who are on dialysis due to severe kidney   disease.
•  Dialysis removes some phosphate from your blood, but it is difficult to remove enough to keep your phosphate levels   balanced.
•  Decreasing blood phosphate levels can help keep your bones strong, prevent unsafe buildup of minerals in your body, and   possibly decrease the risk of heart disease and strokes that can result from high phosphate levels.

•  Stomach upset may occur. If this effect persists or worsens, notify your doctor or pharmacist promptly.
•  If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk   of side effects. Many people using this medication do not have serious side effects.
•  Tell your doctor right away if any of these unlikely but serious side effects occur: stomach/abdominal pain, loss of   appetite, nausea, vomiting, constipation, confusion, dry mouth, increased thirst/urination.
•  A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic   reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

•  Before taking calcium acetate, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
•  This medication should not be used if you have a certain medical condition. Before using this medicine, consult your doctor or     pharmacist if you have: a high blood calcium level (hypercalcemia).
•  Before using this medication, tell your doctor or pharmacist your medical history.
•  During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
•  This medication passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.

• Folic acid is the synthetic form of folate, which is a naturally occurring B vitamin. Folate helps make DNA and other genetic material. It is especially important in prenatal health.
• Folate, also called vitamin B-9, is a B vitamin that naturally occurs in certain foods. Folic acid is the form of folate that manufacturers add to vitamin supplements and fortified foods.

• It helps the body make healthy new red blood cells.
• In its deficiency a person can develop anemia, leading to fatigue, weakness, and a pale complexion.
• It leads to folate deficiency anemia.
• Folate is also important for the synthesis and repair of DNA and other genetic material.
• It is particularly important to get during pregnancy. Folate deficiency during pregnancy can lead to neural tube irregularities, such as spina bifida and anencephaly.
• Folic acid is crucial for early fetal development.
• Neural tube irregularities - Taking folic acid supplements before and during pregnancy will help prevent neural tube irregularities in the fetus.
• It may also reduce the risks of preterm birth, heart irregularities, and cleft palate, among other things.
• Depression - Taking folic acid supplements could make depression medications more effective.
• The Office on Women’s Health recommend that women who are or might become pregnant take 400–800 mcg of folic acid per day, and that people with spina bifida or a family history of neural tube irregularities take 4,000 mcg per day. Those who are breastfeeding should aim to take around 500 mcg per day.
• The body absorbs folic acid from supplements and fortified foods better than the folate from naturally occurring foods.

Skin reactions, seizures, gases problem, diarrhea, irritability, confusion, stomach upset, loss of appetite, and hypersensitivity

It is important to note that folic acid can interact with certain medications.

A person should speak to a doctor before taking folic acid if they have any of the following:

• Epilepsy
• Type 2 diabetes
• Rheumatoid arthritis
• Lupus
• Inflammatory bowel disease (ibd)
• Celiac disease

People undergoing kidney dialysis may also wish to avoid taking folic acid.

• Methylcobalamin/Mecobalamin is a form of vitamin B12 that restores its level in the body thereby helping in treating certain anaemias and nerve problems.
• It is required for the integrity of myelin, neuronal function, proper red blood cell formation and DNA synthesis

• It is used to treat Vitamin B12 deficiency in people with Pernicious Anemia.
• It is a beneficial drug to most of the common disorders like cardiovascular disorders, diabetes, anaemia, hyperhomocysteinemia and degenerative disorders.
• Methylcobalamin helps in the synthesis of neuronal lipids, regeneration of axonal nerves and has neuroprotective activity, which promotes neurons to function properly and thus improves Alzheimer disease, Parkinsonism, Dementia and neuropathic syndromes.
• It is an approved treatment for peripheral neuropathy.
• It also helps in balancing the levels of homocysteine, which is produced in excess can cause inflammation of blood vessels.

• Nausea and vomiting
• Diarrhoea
• Decreased appetite
• Dizziness
• Headache
• Skin rash
• Chest pain and discomfort

• Methylcobalamin can show some serious side effects in patients who might suffer from other conditions.
• Everyone needs to consume this medicine only after clinical consultation. The serious side effects of Methylcobalamin can include the formation of clots in limbs, depleted levels of potassium in the blood, a buildup of fluid in the lungs, heart failure and in some cases, anaphylactic reactions such as swollen tongue and throat, and hives.
• Consuming Methylcobalamin is not advisable for patients suffering from optic atrophy, which is a nerve condition that affects the eye.
• People who are suffering from infections or patients who have a low iron level in their body should be careful before taking Methylcobalamin and should only do so after the consultation of the doctor.
• It is not advised for mothers to consume Methylcobalamin if they are breastfeeding. Mother’s milk is a rich source of Vitamin B12 and consuming additional supplements while breastfeeding can have adverse effects on the baby.

Generic Name: cholecalciferol 

Vitamin D3 is needed for normal absorption of calcium and phosphorus, which is further utilized for development and maintenance of bones and teeth. This makes bones stronger and reduces risk for bone fractures.  Vitamin D3 also has a role in ones nerve, muscle, and immune systems.

People who might need extra vitamin D3 include

•  Older adult
•  Breastfed infants
•  People with dark skin
•  People with certain conditions, such as liver diseases, cystic fibrosis and Crohn's disease
•  People who have obesity or have had gastric bypass surgery

Symptoms of vitamin D3 deficiency include bone pain, muscle weakness, fatigue, and mood changes. Vitamin D3 is used for treating osteoporosis, rickets, osteomalacia, renal osteodystrophy and hypoparathyroidism.

•   nausea
•       vomiting
•         constipation
•         weight loss
•        weakness
•         increased calcium levels (hypercalcemia)

May cause allergic reactions or other problems if contain inactive ingredients such as peanut/soy. Pregnant women or Breastfeeding mothers need to consult their doctors before taking Vitamin D3 supplements.