Panthenol is a multi-functional active ingredient that would be useful in most skincare formulations. Panthenol is a natural chemical compound closely related to vitamin B5. D-Panthenol provides essential nutrients.
 

• D-panthenol has a good clinical track record in helping to heal a wide variety of skin damage, often as a part of a combined therapy. It appears to speed up healing of wounds and burns as well as aid in skin transplantation and scar treatment. The skin healed with the aid of D-panthenol tends to be softer, more elastic and more regular. This may be due to the demonstrated ability of D-panthenol to stimulate the growth of key skin cells (particularly dermal fibroblasts) and possibly remodel this skin matrix.
• D-panthenol also improves superficial skin damage (seen in dry, rough, chafed skin) by helping regenerate/strengthen the epidermis and stratum corneum (outer skin layers) and thus improving the skin's protective barrier. D-panthenol was also shown to reduce irritation/inflammation as well as improve erythema (redness), pruritis (itchiness) and other symptoms.

D- Panthenol can cause allergic reactions.

• D- panthenol (vitamin B5) should preferably be taken with food to avoid stomachupset.
• Do not take D-Panthenol, if you are allergic to it.

Tell your doctor before taking D-Panthenol:

•  if you are pregnant, planning to become pregnant, or are breast-feeding.
•  if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement.
•  if you have allergies to medicines, foods, or other substances.

Vitamin B1 is found in many foods including yeast, cereal grains, beans, nuts, and
meat. It is often used in combination with other B vitamins, and found in many
vitamin B complex products.

It is used for the treatment and prevention of vitamin B1 deficiency. It is also used to
treat Beriberi and Wernicke's encephalopathy.

 Allergic reaction
 Skin irritation
 Cough
 Decreased blood pressure
 Difficulty in swallowing
 Breathlessness
 Facial swelling
 Increased sweating

Vitamin B1 is LIKELY SAFE for pregnant or breast-feeding women if taken in proper
quantity.
Alcoholics and people with cirrhosis often have low levels of Vitamin B1. Nerve pain
in alcoholism can be worsened by Vitamin B1 deficiency. These people might
require Vitamin B1 supplements.
People undergoing hemodialysis treatments might have low levels of Vitamin B1. 
People with heart failure might have low levels of Vitamin B1. 
People that are critically ill such as those that had surgery might have low levels of
Vitamin B1.

• Methylcobalamin/Mecobalamin is a form of vitamin B12 that restores its level in the body thereby helping in treating certain anaemias and nerve problems.
• It is required for the integrity of myelin, neuronal function, proper red blood cell formation and DNA synthesis

• It is used to treat Vitamin B12 deficiency in people with Pernicious Anemia.
• It is a beneficial drug to most of the common disorders like cardiovascular disorders, diabetes, anaemia, hyperhomocysteinemia and degenerative disorders.
• Methylcobalamin helps in the synthesis of neuronal lipids, regeneration of axonal nerves and has neuroprotective activity, which promotes neurons to function properly and thus improves Alzheimer disease, Parkinsonism, Dementia and neuropathic syndromes.
• It is an approved treatment for peripheral neuropathy.
• It also helps in balancing the levels of homocysteine, which is produced in excess can cause inflammation of blood vessels.

• Nausea and vomiting
• Diarrhoea
• Decreased appetite
• Dizziness
• Headache
• Skin rash
• Chest pain and discomfort

• Methylcobalamin can show some serious side effects in patients who might suffer from other conditions.
• Everyone needs to consume this medicine only after clinical consultation. The serious side effects of Methylcobalamin can include the formation of clots in limbs, depleted levels of potassium in the blood, a buildup of fluid in the lungs, heart failure and in some cases, anaphylactic reactions such as swollen tongue and throat, and hives.
• Consuming Methylcobalamin is not advisable for patients suffering from optic atrophy, which is a nerve condition that affects the eye.
• People who are suffering from infections or patients who have a low iron level in their body should be careful before taking Methylcobalamin and should only do so after the consultation of the doctor.
• It is not advised for mothers to consume Methylcobalamin if they are breastfeeding. Mother’s milk is a rich source of Vitamin B12 and consuming additional supplements while breastfeeding can have adverse effects on the baby.