• Vitamin E is essential to the normal functioning of the human body. It plays a central role in your immune system and functions as an antioxidant, neutralizing free radicals that damage cells at the genetic level.
• Vitamin E is fat-soluble, meaning that it is dissolved in fat and able to be stored in the liver and fatty tissues of the body.
   

• Vitamin E acts as an antioxidant (i.e., an inhibitor of oxidation processes) in body tissues. It protects unsaturated fats in the body from oxidation by peroxides and other free radicals.  It also acts as an protection of polyunsaturated fatty acids, cell membranes.
• The vitamin is used commercially as an antioxidant to retard the rancidification of fats, especially vegetable oils.
• Vitamin E aids in the transmission of electrical signals between nerve cells (neurons) of the brain and body.
• Vitamin E is integral to eye health, aiding in the self-repair of the retina, cornea, and uvea (the pigmented portion of the eye).
• Vitamin E can aid in scar healing by hydrating the skin, inhibiting collagen production, and reducing inflammation that can lead to tissue damage.
   

Vitamin E supplements rarely cause any harm if taken at the recommended daily dose.
But sometimes lower doses can trigger side effects like

•  nausea,
•  vomiting,
•  stomach pain,
•  diarrhea.
•  Slow down blood clotting

• Vitamin E deficiency is considered rare in the developed world, except in premature babies with low birth weight or in people with rare genetic disorders such as abetalipoproteinemia or ataxia with vitamin E deficiency.
• VitaminE can neither treat nor prevent liver disease but may help slow its progression.
• VitaminE can slow blood clotting and may need to be avoided in people taking blood thinners like Coumadin (warfarin) or Plavix (clopidogrel).
• VitaminE supplements should also be avoided in people with a history of heart attacks, stroke, bleeding disorders, or head and neck cancers.
• VitaminE supplements are presumed to be safe during pregnancy and breastfeeding.

Octinoxate, also called Octylmethoxycinnamate or OMC, is a chemical commonly used in cosmetic and skin care products around the world. Octinoxate is in a class of chemicals made by mixing an organic acid with an alcohol. In this case, sulfuric acid and methanol combined make octinoxate. Octinoxate is a component of sunscreen. It filters the UV rays from the sun by absorbing through the skin. This is how it protects the skin from sunburn.

Octinoxate is used in the treatment of nutritional deficiencies. It is primarily used in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage. It is also used to reduce the appearance of scars.

Some research has found that octinoxate can cause adverse skin reactions, like acne and contact dermatitis in humans. But this has only been shown to occur in a minority of people who have specific skin allergies.
Few side effects of octinoxate are:

• Anal irritation,
• Skin rash,
• Erythema (skin redness)

• Avoid using the cream on irritated skin.
• You may be monitored for hormonal levels as octinoxate may have a negative impact on the endocrine system. Do not take if allergic to octinoxate or any of its ingredients.

Kojic Acid is found naturally in many species of fungi and is also the byproduct made during the fermentation of Sake.
Kojic acid is an anti-pigmentation medicine. It works by suppressing the formation of melanin, a pigment that gives color to the skin.

• Kojic Acid helps in lightening visible spots marks.
• Kojic Acid serves a number of functions beyond skin brightening.
• Kojic Acid is antibacterial, which explains its frequent presence in acne skincare formulations. Because it acts as a skin lightener, it's an effective ingredient for post inflammation hyperpigmentation that can occur from acne lesions. 

• Dry skin,
• Skin burn,
• Skin peeling,
• Erythema (skin redness)

•  It should always be used along with sun-avoidance measures, like using sunscreens and wearing protective clothing.
•  Avoid getting it in your eyes or mouth. If this happens, rinse with water immediately.
•  Do not apply on broken or infected areas of skin. Discontinue use if you experience irritation or allergy and consult your doctor.
•  If you experience any redness, rashes, irritation or stinging sensation when using Kojic Acid, stop using it immediately and consult your doctor.