Benfotiamine is a derivative of vitamin B1. Derived from thiamine, this medication is
used as a dietary supplement. It helps to raise tissue and blood levels of thiamine,
which then helps to protect the body from any med conditions arising from low
levels of thiamine such as heart and nerve disorders. It also helps against diabetic
neuropathy.The drug is easily absorbed through cell membranes, thus making it
easier for it to be transported to the cells that most require it.

It is used for the treatment and prevention of vitamin B1 deficiency that cannot be
corrected through dietary modifications. It may also be used for the treatment of
neuropathies and cardiovascular disorders caused due to vitamin B1 deficiency. It
may also be used for the treatment of Beriberi and Wernicke's encephalopathy.

 Cough
 Difficulty in swallowing
 Itching and skin rash
 Swelling of face, lips, eyelids, or tongue
 Difficulty in breathing
 Nausea
 Weight gain
 Burning sensation
 Headache
 Sleepiness

This medicine is not recommended for use in pregnant and breastfeeding women
unless necessary.

This medicine may interact with many other medicines and may cause severe
adverse effects.

• Vitamin E is essential to the normal functioning of the human body. It plays a central role in your immune system and functions as an antioxidant, neutralizing free radicals that damage cells at the genetic level.
• Vitamin E is fat-soluble, meaning that it is dissolved in fat and able to be stored in the liver and fatty tissues of the body.
   

• Vitamin E acts as an antioxidant (i.e., an inhibitor of oxidation processes) in body tissues. It protects unsaturated fats in the body from oxidation by peroxides and other free radicals.  It also acts as an protection of polyunsaturated fatty acids, cell membranes.
• The vitamin is used commercially as an antioxidant to retard the rancidification of fats, especially vegetable oils.
• Vitamin E aids in the transmission of electrical signals between nerve cells (neurons) of the brain and body.
• Vitamin E is integral to eye health, aiding in the self-repair of the retina, cornea, and uvea (the pigmented portion of the eye).
• Vitamin E can aid in scar healing by hydrating the skin, inhibiting collagen production, and reducing inflammation that can lead to tissue damage.
   

Vitamin E supplements rarely cause any harm if taken at the recommended daily dose.
But sometimes lower doses can trigger side effects like

•  nausea,
•  vomiting,
•  stomach pain,
•  diarrhea.
•  Slow down blood clotting

• Vitamin E deficiency is considered rare in the developed world, except in premature babies with low birth weight or in people with rare genetic disorders such as abetalipoproteinemia or ataxia with vitamin E deficiency.
• VitaminE can neither treat nor prevent liver disease but may help slow its progression.
• VitaminE can slow blood clotting and may need to be avoided in people taking blood thinners like Coumadin (warfarin) or Plavix (clopidogrel).
• VitaminE supplements should also be avoided in people with a history of heart attacks, stroke, bleeding disorders, or head and neck cancers.
• VitaminE supplements are presumed to be safe during pregnancy and breastfeeding.

Ascorbic acid (vitamin C) is a water-soluble vitamin. It occurs as a white or slightly yellow crystal or powder with a slight acidic taste. It is an antiscorbutic product. On exposure to light, it gradually darkens. In the dry state, it is reasonably stable in air, but in solution it rapidly oxidizes. Ascorbic acid (vitamin c) is freely soluble in water; sparingly soluble in alcohol; insoluble in chloroform, in ether, and in benzene. The chemical name of ascorbic acid (vitamin c) is L-ascorbic acid (vitamin c)

• Vitamin C is recommended for the prevention and treatment of scurvy.
• Symptoms of mild deficiency may include faulty bone and tooth development, gingivitis, bleeding gums, and loosened teeth. Febrile states, chronic illness, and infection (pneumonia, whooping cough, tuberculosis, diphtheria, sinusitis, rheumatic fever, etc.) increase the need for ascorbic acid (vitamin c).

Less common or rare- with high doses

•  Diarrhea
•  dizziness or faintness (with the injection only)
•  flushing or redness of skin
•  headache
•  increase in urination (mild)
•  nausea or vomiting
•  stomach cramps

• Diabetics, patients prone to recurrent renal calculi, those undergoing stool occult blood tests, and those on sodium-restricted diets or anticoagulant therapy should not take excessive doses of vitamin C over an extended period of time.
• Too-rapid intravenous injection is to be avoided.
• Diabetics taking more than 500 mg vitamin C daily may obtain false readings of their urinary glucose test.