• It is an essential cofactor for many enzymes related to energy metabolism, and activates the insulin-signaling cascade to help lower blood sugar.
• Alpha-lipoic converts blood sugar (glucose) into energy using oxygen, a process referred to as aerobic metabolism. Alpha-lipoic acid is also considered an antioxidant, meaning that it can neutralize harmful compounds called free radicals that damage cells at the genetic level.

• It has long been presumed that alpha-lipoic acid can aid in the control of glucose by increasing the speed in which the blood sugar is metabolized. This could potentially aid in the treatment of diabetes
• It is believed by some that alpha-lipoic acid can effectpeople with diabetic neuropathy,
• Alpha-lipoic acid's ability to enhance calorie burning and promote weight loss has been exaggerated by many diet gurus and supplements manufacturers. 
• Alpha-lipoic acid has long been believed to influence weight and health by altering the lipid (fat) composition in the blood.
• Cosmetics manufacturers often like to boast that their products benefit from the anti-aging properties of alpha-lipoic acid.

•  Nausea,
•  Abdominal pain,
•  Allergic reaction,
•  Diarrhea,
•  Vertigo,
•  Vomiting
•  muscle cramp,
•  a tingling "pins and needles" sensation.

• Food decreases the amount of alpha lipoic acid in the body; hence it should be taken on empty stomach about 1 hour before or 2 hours after consuming food.
• Do not take alpha lipoic acid supplements on your own and as a sole treatment for diabetes, complications of diabetes and other conditions in which benefit may be claimed, as these diseases require proper medical treatment.

Coenzyme Q10 is most commonly used for conditions that affect the heart such as heart failure and fluid build up in the body, chest pain, and high blood pressure. It is also used for preventing migraine headache, Parkinson disease, and many other conditions.

Coenzyme Q10 is a vitamin-like substance found throughout the body, but especially in the heart, liver, kidney, and pancreas.

Major &Minor side effects of Coenzyme Q10

• Stomach upset
• Nausea
• Loss of appetite
• Vomiting
• Diarrhea
• Allergic skin rashes
• Low blood pressure

This medicine is safe when taken by mouth appropriately during pregnancy.

This medicine is safe to be taken by children under medical supervision.

People undergoing chemotherapy with a class of drugs called alkylating agents should use coenzyme Q10 with caution.

Coenzyme Q10 might lower blood pressure.

Cigarette smoking depletes the amount of coenzyme Q10 stored by the body.

Coenzyme Q10 might interfere with blood pressure control during and after surgery.

• Vitamin E is essential to the normal functioning of the human body. It plays a central role in your immune system and functions as an antioxidant, neutralizing free radicals that damage cells at the genetic level.
• Vitamin E is fat-soluble, meaning that it is dissolved in fat and able to be stored in the liver and fatty tissues of the body.
   

• Vitamin E acts as an antioxidant (i.e., an inhibitor of oxidation processes) in body tissues. It protects unsaturated fats in the body from oxidation by peroxides and other free radicals.  It also acts as an protection of polyunsaturated fatty acids, cell membranes.
• The vitamin is used commercially as an antioxidant to retard the rancidification of fats, especially vegetable oils.
• Vitamin E aids in the transmission of electrical signals between nerve cells (neurons) of the brain and body.
• Vitamin E is integral to eye health, aiding in the self-repair of the retina, cornea, and uvea (the pigmented portion of the eye).
• Vitamin E can aid in scar healing by hydrating the skin, inhibiting collagen production, and reducing inflammation that can lead to tissue damage.
   

Vitamin E supplements rarely cause any harm if taken at the recommended daily dose.
But sometimes lower doses can trigger side effects like

•  nausea,
•  vomiting,
•  stomach pain,
•  diarrhea.
•  Slow down blood clotting

• Vitamin E deficiency is considered rare in the developed world, except in premature babies with low birth weight or in people with rare genetic disorders such as abetalipoproteinemia or ataxia with vitamin E deficiency.
• VitaminE can neither treat nor prevent liver disease but may help slow its progression.
• VitaminE can slow blood clotting and may need to be avoided in people taking blood thinners like Coumadin (warfarin) or Plavix (clopidogrel).
• VitaminE supplements should also be avoided in people with a history of heart attacks, stroke, bleeding disorders, or head and neck cancers.
• VitaminE supplements are presumed to be safe during pregnancy and breastfeeding.

Omega-3 fatty acids can improve your cardiovascular health.

Omega-3 fatty acids are a type of fat the body cannot make on its own. They are an essential fat, which means they are needed to survive.

Major &Minor side effects of Omega -3 fatty acid

• Raise levels of high-density lipoprotein (HDL/“good” cholesterol).
• Lower blood pressure.
• burping.
• heartburn.
• stomach pain or discomfort.
• joint pain.
• vomiting.
• constipation.
• diarrhea.
• nausea.

Before taking omega-3 fatty acids, tell your doctor if you are allergic to them; or to fish; or if you have any other allergies.

This product may contain inactive ingredients (such as peanut/soy), which can cause allergic reactions or other problems.

During pregnancy, this medication should be used only when clearly needed.