SPEGRA is a fixed-dose combination medication containing Tenofovir, Emtricitabine, and Dolutegravir. It is used for the treatment of HIV-1 infection in adults and adolescents above 12 years of age. This combination medication helps to suppress the replication of the virus and reduce the viral load, thereby improving immune function and slowing down the progression of the disease. It is usually prescribed as part of a complete antiretroviral therapy regimen.

• Treatment of HIV-1 infection
• Improves immune function
• Reduces viral load

• Headache
• Diarrhea
• Nausea
• Insomnia
• Dizziness
• Skin rash

Take SPEGRA orally as directed by your doctor. Do not crush, chew, or break the tablets. It is important to adhere to the prescribed dosage and follow the recommended dosing schedule.

• Pregnancy - SPEGRA should be used with caution during pregnancy. Consult your doctor for evaluation of the risks and benefits before initiating or continuing treatment.
• Alcohol - There are no known interactions between alcohol and SPEGRA. However, it is advisable to consult your doctor regarding alcohol consumption.
• Old Age - No specific precautions need to be taken while using SPEGRA in the elderly population. However, individualized dosing adjustments may be required based on renal function.
• Breast Feeding - SPEGRA is usually not recommended while breastfeeding. Consult your doctor for advice on alternative medications.
• Children - SPEGRA is safe for use in adolescents above 12 years of age. However, the dosage may vary based on the individual's weight and renal function. Consult your doctor for the appropriate dosage.

• Store at room temperature (20-25°C) -
• Protect from moisture and light -
• Keep out of reach of children -

• Drug-Drug - There may be significant drug-drug interactions with other medications, including antacids, antiepileptics, and certain antiviral drugs. Inform your doctor about all the medications you are currently taking.
• Drug-Food - There are no known significant drug-food interactions with SPEGRA.
• Drug-Disease - Patients with a history of liver or kidney disease may require special monitoring while using SPEGRA. Consult your doctor for appropriate dosage adjustments.

• Q. What should I do if I miss a dose of SPEGRA?
  If you miss a dose, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.
• Q. Can I develop resistance to SPEGRA?
  It is possible to develop resistance to SPEGRA if not taken consistently and as prescribed. It is important to adhere to the recommended dosing schedule to maximize the effectiveness of the medication.
• Q. Are there any long-term side effects of using SPEGRA?
  Long-term use of SPEGRA may be associated with potential side effects such as bone loss or kidney problems. Regular monitoring and appropriate medical follow-up are necessary to mitigate these risks.
• Q. Is it safe to switch to SPEGRA if I am already taking another HIV medication?
  Switching to SPEGRA should only be done under the supervision of a healthcare professional. There may be specific considerations and potential interactions with other HIV medications that need to be evaluated.
• Q. Can I stop taking SPEGRA once my viral load becomes undetectable?
  It is important to continue taking SPEGRA as prescribed, even if your viral load becomes undetectable. Discontinuing the medication without medical guidance can lead to viral rebound and the development of drug resistance.