• CALCITRIOL is a man-made form of vitamin D. It helps your body keep the proper levels of calcium and phosphorus and maintain healthy bones and teeth.
• It raises Vitamin D levels in your blood. This, in turn, raises calcium levels in your blood by helping you absorb more calcium from your intestine

• Calcitriol is a synthetic version of Vitamin D3 used to treat calciumdeficiency with hypoparathyroidism (decreased functioning of the parathyroid glands) and metabolic bone disease in people with chronic kidney failure.
• Calcitriol is used in the treatment of calcium deficiency and postmenopausal osteoporosis.

• Constipation
• Dry Mouth
• Headache
• Loss Of Appetite
• Metallic Taste
• Stomach Upset
• Allergic Reactions Like Skin Rash, Itching Or Hives, Swelling Of The Face, Lips, Or Tongue
• Bone Pain
• Increased Thirst
• Increased Urination (Especially At Night)
• Irregular Heartbeat, High Blood Pressure
• Redness, Blistering, Peeling Or Loosening Of The Skin, Including Inside The Mouth
• Seizures
• Unexpected Weight Loss
• Unusually Weak Or Tired

• You should not use calcitriol if you have high levels of calcium or vitamin D in your blood, or you have had an allergic reaction to calcitriol or other forms of vitamin D.

• It is a laxative (osmotic-type) that is thought to work by drawing water into the intestines, an effect that helps to cause movement of the intestines.
• Magnesium Hydroxide is an antacid that neutralises excess acid in stomach.

Magnesium Hydroxide is a stool softener used in the treatment of constipation; it prevents dry and hard stools. It is also used to relieve symptoms such as heartburn, sour stomach, flatulence, etc.

• Stomach upset
• Nausea and Vomiting
• Diarrhea
• Stomach cramps
• Muscle weakness

• This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects.
• Use of this medicine may increase the magnesium levels in the blood. The risk is especially higher in patients suffering from kidney diseases. Report any symptoms such as flushing of the skin, increased thirst, difficulty in breathing, changes in heart rate, etc. to the doctor immediately.
• Do not take it for more than 2 weeks, unless otherwise prescribed by the doctor.
• Avoid Magnesium Hydroxide, if you show signs of appendicitis or inflammed bowel (such as lower abdominal pain, cramping, bloating, nausea, vomiting). Please consult your doctor.
• Do not take the Magnesium Hydroxide at least 2 hours before or after taking other medicines. It may interact with other medicines.

• Folic acid is the synthetic form of folate, which is a naturally occurring B vitamin. Folate helps make DNA and other genetic material. It is especially important in prenatal health.
• Folate, also called vitamin B-9, is a B vitamin that naturally occurs in certain foods. Folic acid is the form of folate that manufacturers add to vitamin supplements and fortified foods.

• It helps the body make healthy new red blood cells.
• In its deficiency a person can develop anemia, leading to fatigue, weakness, and a pale complexion.
• It leads to folate deficiency anemia.
• Folate is also important for the synthesis and repair of DNA and other genetic material.
• It is particularly important to get during pregnancy. Folate deficiency during pregnancy can lead to neural tube irregularities, such as spina bifida and anencephaly.
• Folic acid is crucial for early fetal development.
• Neural tube irregularities - Taking folic acid supplements before and during pregnancy will help prevent neural tube irregularities in the fetus.
• It may also reduce the risks of preterm birth, heart irregularities, and cleft palate, among other things.
• Depression - Taking folic acid supplements could make depression medications more effective.
• The Office on Women’s Health recommend that women who are or might become pregnant take 400–800 mcg of folic acid per day, and that people with spina bifida or a family history of neural tube irregularities take 4,000 mcg per day. Those who are breastfeeding should aim to take around 500 mcg per day.
• The body absorbs folic acid from supplements and fortified foods better than the folate from naturally occurring foods.

Skin reactions, seizures, gases problem, diarrhea, irritability, confusion, stomach upset, loss of appetite, and hypersensitivity

It is important to note that folic acid can interact with certain medications.

A person should speak to a doctor before taking folic acid if they have any of the following:

• Epilepsy
• Type 2 diabetes
• Rheumatoid arthritis
• Lupus
• Inflammatory bowel disease (ibd)
• Celiac disease

People undergoing kidney dialysis may also wish to avoid taking folic acid.