• Vitamin E is essential to the normal functioning of the human body. It plays a central role in your immune system and functions as an antioxidant, neutralizing free radicals that damage cells at the genetic level.
• Vitamin E is fat-soluble, meaning that it is dissolved in fat and able to be stored in the liver and fatty tissues of the body.
   

• Vitamin E acts as an antioxidant (i.e., an inhibitor of oxidation processes) in body tissues. It protects unsaturated fats in the body from oxidation by peroxides and other free radicals.  It also acts as an protection of polyunsaturated fatty acids, cell membranes.
• The vitamin is used commercially as an antioxidant to retard the rancidification of fats, especially vegetable oils.
• Vitamin E aids in the transmission of electrical signals between nerve cells (neurons) of the brain and body.
• Vitamin E is integral to eye health, aiding in the self-repair of the retina, cornea, and uvea (the pigmented portion of the eye).
• Vitamin E can aid in scar healing by hydrating the skin, inhibiting collagen production, and reducing inflammation that can lead to tissue damage.
   

Vitamin E supplements rarely cause any harm if taken at the recommended daily dose.
But sometimes lower doses can trigger side effects like

•  nausea,
•  vomiting,
•  stomach pain,
•  diarrhea.
•  Slow down blood clotting

• Vitamin E deficiency is considered rare in the developed world, except in premature babies with low birth weight or in people with rare genetic disorders such as abetalipoproteinemia or ataxia with vitamin E deficiency.
• VitaminE can neither treat nor prevent liver disease but may help slow its progression.
• VitaminE can slow blood clotting and may need to be avoided in people taking blood thinners like Coumadin (warfarin) or Plavix (clopidogrel).
• VitaminE supplements should also be avoided in people with a history of heart attacks, stroke, bleeding disorders, or head and neck cancers.
• VitaminE supplements are presumed to be safe during pregnancy and breastfeeding.

Vitamin B1 is found in many foods including yeast, cereal grains, beans, nuts, and
meat. It is often used in combination with other B vitamins, and found in many
vitamin B complex products.

It is used for the treatment and prevention of vitamin B1 deficiency. It is also used to
treat Beriberi and Wernicke's encephalopathy.

 Allergic reaction
 Skin irritation
 Cough
 Decreased blood pressure
 Difficulty in swallowing
 Breathlessness
 Facial swelling
 Increased sweating

Vitamin B1 is LIKELY SAFE for pregnant or breast-feeding women if taken in proper
quantity.
Alcoholics and people with cirrhosis often have low levels of Vitamin B1. Nerve pain
in alcoholism can be worsened by Vitamin B1 deficiency. These people might
require Vitamin B1 supplements.
People undergoing hemodialysis treatments might have low levels of Vitamin B1. 
People with heart failure might have low levels of Vitamin B1. 
People that are critically ill such as those that had surgery might have low levels of
Vitamin B1.

DHA is used as a supplement for premature babies and as an ingredient in baby formula during the first year of life to promote better mental development. It is also used in infant formula to prevent lung diseases, allergic diseases such as eczema or hay fever, and diarrhea.

In some cases, DHA is used in combination with arachidonic acid.

DHA is also taken by mouth alone or along with EPA to improve mental function in healthy people or those with mental impairment.

It is also used to improve mental function in people with dementia or age-related mental decline.

 It is also taken by mouth for attention deficit-hyperactivity disorder (ADHD), depression, aggressive behavior, Alzheimer's disease, autism, and to prevent relapse in schizophrenic patients who stop taking antipsychotic medication.

Docosahexaenoic acid (DHA) belongs to the class of medications called as nutritional supplements. DHA plays a vital role in the brain development. DHA decreases cholesterol and triglyceride levels, inhibits platelet aggregation and oxidation of LDL, decreases the synthesis of inflammatory markers such as prostaglandins. Overall, DHA plays a vital role in reducing the heart and circulatory disease risks.

Major & minor side effects for Docosahexaenoic acid

• Bad breath
• Heartburn
• Nausea
• Weight gain
• Allergy

Seek immediate medical attention if you experience any allergic symptoms.

Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding.

Do not take if allergic to DHA or any of its ingredients.

Do not take if having problem with aspirin-sensitivity and hypertension.

Do not take if allergic to fish products.

Eicosapentaenoic acid is used in combination with docosahexaenoic acid (DHA) in fish oil preparations for a variety of conditions, including preventing and reversing heart disease, and decreasing irregular heartbeats; as well as asthma, cancer, menstrual problems, hot flashes, hay fever, lung diseases, lupus, and kidney disease caused by an immune reaction.

The combination is also used for migraine headache prevention in adolescents, skin infections, Behçet's syndrome, high cholesterol, high blood pressure, psoriasis, Raynaud's syndrome, rheumatoid arthritis, Crohn's disease, and ulcerative colitis.

Eicosapentaenoic acid is long-chain n-3 polyunsaturated fatty acids, which compete with arachidonic acid for inclusion in cyclo-oxygenase and lipoxygenase pathways.

It's actions include hypolipidaemic action (especially a reduction in plasma triglycerides) by reducing very-low-density lipoproteins; anti-inflammatory action, attributed to effects on leukotriene synthesis; and antiplatelet effect, attributed to effects on prostanoid synthesis, which promote vasodilatation, reduction in platelet aggregation, increased bleeding time and decreased platelet counts.

• Nausea
• Gastrointestinal discomfort
• Burping
• Vomiting
• Joint,back and muscle pain
• Diarrhea
• Nosebleed

When used in amounts greater than 3 grams per day, eicosapentaenoic acid can thin the blood and increase the risk for bleeding.

If you are sensitive to aspirin, eicosapentaenoic acid might affect your breathing.

Eicosapentaenoic acid might lower blood pressure.

Lycopene is a powerful antioxidant that may help protect cells from damage. Hence, it is used for high blood pressure, high cholesterol, cancer, and many other conditions.

Used to treat prostate cancer, leukoplakia, asthma and heart disease.

Discoloration of the skin - Lycopenemia

•  Avoid if pregnant
•  It might increase the risk of bleeding during and after surgery. Stop using lycopene supplements at least 2 weeks before a scheduled surgery.
•  Those taking medication for low blood pressure should not take lycopene.

Coenzyme Q10 is most commonly used for conditions that affect the heart such as heart failure and fluid build up in the body, chest pain, and high blood pressure. It is also used for preventing migraine headache, Parkinson disease, and many other conditions.

Coenzyme Q10 is a vitamin-like substance found throughout the body, but especially in the heart, liver, kidney, and pancreas.

Major &Minor side effects of Coenzyme Q10

• Stomach upset
• Nausea
• Loss of appetite
• Vomiting
• Diarrhea
• Allergic skin rashes
• Low blood pressure

This medicine is safe when taken by mouth appropriately during pregnancy.

This medicine is safe to be taken by children under medical supervision.

People undergoing chemotherapy with a class of drugs called alkylating agents should use coenzyme Q10 with caution.

Coenzyme Q10 might lower blood pressure.

Cigarette smoking depletes the amount of coenzyme Q10 stored by the body.

Coenzyme Q10 might interfere with blood pressure control during and after surgery.