Deferasirox is an iron chelator (binder). Deferasirox binds to iron and removes it
from the bloodstream, which is then excreted mainly in the stools. This reduces the
risk of organ damage.
Deferasirox is used to treat iron overload caused by blood transfusions in adults and
children at least 2 years old.
Deferasirox is also used to treat chronic iron overload syndrome caused by a genetic
blood disorder in adults and children who are at least 10 years
Nausea,
Headache,
Vomiting,
Rash,
Indigestion,
Abdominal pain,
Constipation,
Itching,
Increased liver enzymes,
Abdominal distension,
Diarrhea
This medicine is not recommended for use in pregnant and breastfeeding women
unless absolutely necessary.
This medicine may interact with many other medicines and may cause severe
adverse effects.
Use of this medicine in children is condition specific. For treating iron overload, it
should not be used in children less than 2 years of age.
Your doctor may conduct regular tests to obtain the serum ferritin and liver iron
concentration values during treatment with this medicine.
This medicine should be used with caution in patients with an impaired liver
function, impaired kidney function and in eldery patients due to the increased risk
of severe adverse effects.
Use of this medicine may cause severe and life-threatening allergic reactions in
some patients.
This medicine should be used with extreme caution in patients with a history of
gastrointestinal disorders including gastric bleeding, ulceration, or blockage since it
may worsen the patient's condition.