Generic Name: cholecalciferol 

Vitamin D3 is needed for normal absorption of calcium and phosphorus, which is further utilized for development and maintenance of bones and teeth. This makes bones stronger and reduces risk for bone fractures.  Vitamin D3 also has a role in ones nerve, muscle, and immune systems.

People who might need extra vitamin D3 include

•  Older adult
•  Breastfed infants
•  People with dark skin
•  People with certain conditions, such as liver diseases, cystic fibrosis and Crohn's disease
•  People who have obesity or have had gastric bypass surgery

Symptoms of vitamin D3 deficiency include bone pain, muscle weakness, fatigue, and mood changes. Vitamin D3 is used for treating osteoporosis, rickets, osteomalacia, renal osteodystrophy and hypoparathyroidism.

•   nausea
•       vomiting
•         constipation
•         weight loss
•        weakness
•         increased calcium levels (hypercalcemia)

May cause allergic reactions or other problems if contain inactive ingredients such as peanut/soy. Pregnant women or Breastfeeding mothers need to consult their doctors before taking Vitamin D3 supplements.

• Vitamin E is essential to the normal functioning of the human body. It plays a central role in your immune system and functions as an antioxidant, neutralizing free radicals that damage cells at the genetic level.
• Vitamin E is fat-soluble, meaning that it is dissolved in fat and able to be stored in the liver and fatty tissues of the body.
   

• Vitamin E acts as an antioxidant (i.e., an inhibitor of oxidation processes) in body tissues. It protects unsaturated fats in the body from oxidation by peroxides and other free radicals.  It also acts as an protection of polyunsaturated fatty acids, cell membranes.
• The vitamin is used commercially as an antioxidant to retard the rancidification of fats, especially vegetable oils.
• Vitamin E aids in the transmission of electrical signals between nerve cells (neurons) of the brain and body.
• Vitamin E is integral to eye health, aiding in the self-repair of the retina, cornea, and uvea (the pigmented portion of the eye).
• Vitamin E can aid in scar healing by hydrating the skin, inhibiting collagen production, and reducing inflammation that can lead to tissue damage.
   

Vitamin E supplements rarely cause any harm if taken at the recommended daily dose.
But sometimes lower doses can trigger side effects like

•  nausea,
•  vomiting,
•  stomach pain,
•  diarrhea.
•  Slow down blood clotting

• Vitamin E deficiency is considered rare in the developed world, except in premature babies with low birth weight or in people with rare genetic disorders such as abetalipoproteinemia or ataxia with vitamin E deficiency.
• VitaminE can neither treat nor prevent liver disease but may help slow its progression.
• VitaminE can slow blood clotting and may need to be avoided in people taking blood thinners like Coumadin (warfarin) or Plavix (clopidogrel).
• VitaminE supplements should also be avoided in people with a history of heart attacks, stroke, bleeding disorders, or head and neck cancers.
• VitaminE supplements are presumed to be safe during pregnancy and breastfeeding.

• Vitamin A is vital for a healthy immune system, bone growth, vision, cell recognition and reproduction. Vitamin A often works as an antioxidant, fighting cell damage, but it also has many other uses. It has a vital role in the formation of heart, lungs, and kidney.
• Other functions of vitamin A include the formation and maintenance of teeth, bones, soft tissue, white blood cells, the immune system and mucus membranes. 
• Most people get enough vitamin A from their diets. However, a doctor might suggest vitamin A supplements to people who have vitamin A deficiencies. People most likely to have vitamin A deficiency are those with diseases (such as digestive disorders) or very poor diets.

• Vitamin A is used for improving the eyesight, maintaining cells of the skin and the lining of the digestive, urinary and respiratory tracts.
• It also helps in the formation of red and white blood cells in our body that are important to carry out the various essential functions of our body.
• Topical and oral retinoids are common prescription treatments for acne and other skin conditions, including wrinkles. 
• Oral vitamin A is also used as a treatment for measles and dry eye in people with low levels of vitamin A. 
• Vitamin A is also used for a specific type of leukemia.
• Vitamin A has been studied as a treatment for many other conditions, including cancers, cataracts, and HIV. However, the results are inconclusive.

• Night blindness
• A higher risk of infections, especially in the throat, chest, and abdomen
• Follicular hyperkeratosis, leading to dry, bumpy skin.
• Fertility issues
• Delayed growth in children
• Symptoms of vitamin A toxicity include dry skin, joint pain, vomiting, headaches, confusion.

• If you take too much of Vitamin A, it can lead to birth defects, abnormalities of the liver and disorders of the central nervous system.
• It can also decrease bone mineral density, leading to an increased risk of osteoporosis.
• This is because an excess of Vitamin A suppresses the building up of bones and increases its breakdown.
• The rate of calcium absorption by Vitamin D can also get affected due to excess of Vitamin A. Therefore, it is advised to use Vitamin A only as directed by your doctor.
• Interactions. Vitamin A supplements may interact with some birth control pills, blood thinners (Coumadin), acne medicines (isotretinoin), cancer treatments, and many other drugs.
• People who drink heavily or have kidney or liver disease shouldn’t take vitamin A supplements without talking to a doctor.

Biotin is a B complex vitamin used as a nutritional supplementation for dietary shortage or imbalance which may cause hair loss or total alopecia, brittle nails, skin rash in infants, and mild depression.

Biotin is a form of vitamin B that provides essential nutrients.

Major & minor side effects for Biotin

• Hypersensitivity
• Stomach discomfort and pain
• Skin rash

This medicine is considered safe for consumption by pregnant and breastfeeding women.

Use of this medicine in children should be done only under your doctor's supervision.

The effect of therapy with Biotin may occur 3 to 6 months after starting the therapy.

Dialysis patients may require a higher dose due to drug removal during dialysis.