Glucosamine is a proteoglycan synthesis stimulator which relieves osteoarthritis symptoms. It helps in the formation of cartilage (the soft tissue that cushions the joints) and keep the joints lubricated for better movement and flexibility.
 

•  Glucosamine sulfate are often used as natural remedies for osteoarthritis.
• Glucosamine sulfate can help control osteoarthritis by protecting against the breakdown of cartilage. 
• Glucosamine is touted as a natural remedy for interstitial cystitis, temporomandibular joint disorder, and glaucoma.

•  bloating
•  constipation
•  diarrhea
•  gas
•  heartburn
•  indigestion
•  nausea
•  stomach upset

In rare cases, use of glucosamine may cause such side effects as drowsiness, skin
reactions, vomiting, headache, elevated blood pressure and heart rate, and
palpitations.

•  Do not take glucosamine, if you are allergic to glucosamine or shell fish.
•  Avoid taking glucosamine, if you are pregnant or breast feeding.
•  Doctor’s advice should be considered in case of patients with following history of disease conditions: diabetes; high cholesterol or triglycerides; cancer; liver disease; asthma or breathing disorder.
•  Do not continue the glucosamine, if you are having surgery.

• Sodium Hyaluronate is the salt form of hyaluronic acid. It works by reducing the friction in the joints and helps them to work smoothly. It may work by acting as a lubricant and shock absorber in the joint, helping the knee to move smoothly, thereby lessening pain.
• Hyaluronic acid is also one of the most popular ingredients in the cosmetic industry, offering powerful absorption and hydration properties. 
   

This medication is used to treat knee pain in patients with joint inflammation (osteoarthritis). It is usually used in patients who have not responded to other treatments such as acetaminophen, exercise, or physical therapy. Also used as a Treatment to coat the bladder lining when treating conditions like interstitial cystitis. 

• The topical form of this medicine is used to treat skin conditions such as bed sores, diabetic foot ulcers, burn wounds, surgical incisions, dry or scaly skin, cuts, skin irritations, etc. 
• The ophthalmic form of this medicine is used to prevent eye dryness. It may also be used during eye surgeries to protect eye tissues from mechanical stress. It’s often used in cosmetic products to help the skin absorb and retain more moisture, which can create a plumping effect that results in smooth, supple skin.

•  Diarrhea
•  Headache
•  Itching of skin
•  Loss of appetite
•  Stomach pain
•  Swelling of the knee
• Swelling of eyelids, face, lips
•  Injection site pain
•  Fever
•  Skin discoloration
•  Weakness
•  Change in eyesight
•  Eye pain
•  Eye irritation

In cases of an allergic reaction when used for skin, you may experience hives, severe itching, or swelling of eyes, face, lips, and tongue. 

• Do not strain your knee joint for two days after receiving Sodium Hyaluronate. Avoid activities such as strenuous sports and exercise, or standing on your feet for a long time.
• Inform your doctor if knee pain or swelling continues for a long time or becomes worse after receiving the medication.
• Before using this medication, tell your doctor or pharmacist your medical history, especially of: kneejoint infections, skin infections/problems in the area around the injection site, circulation problems in the legs.

• METHYLSULFONYLMETHANE (MSM) is an herbal product or dietary supplement.
• Methyl Sulfonyl Methane is a non-steroidal anti-inflammatory drugs (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Some believe that the substance can treat a wide range of health problems, mostnotably arthritis.

Methylsulfonylmethane is used in the treatment of various conditions such as osteoarthritis, tendinitis, musculoskeletal pain, rheumatoid arthritis etc. It is generally used in combination with other medicines for a more effective treatment.

• Diarrhea or constipation
•  Nausea
•  Bloating
•  Headache
•  Fatigue
•  Insomnia

• Take it with food or milk to prevent upset stomach.
•  Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
•  Inform your doctor if you have a history of heart disease or stroke.
•  Avoid consuming alcohol while taking Methyl Sulfonyl Methane as it can increase your risk of stomach problems.
•  Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.
•  This supplement is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Indicated for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN), to maintain chromium serum levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms.

Chromium helps to maintain normal glucose metabolism and peripheral nerve function. Chromium increases insulin binding to cells, increases insulin receptor density and activates insulin receptor kinase leading to enhanced insulin sensitivity 

Consult your Doctor for the same

Consult your Doctor for the same