• Vitamin E is essential to the normal functioning of the human body. It plays a central role in your immune system and functions as an antioxidant, neutralizing free radicals that damage cells at the genetic level.
• Vitamin E is fat-soluble, meaning that it is dissolved in fat and able to be stored in the liver and fatty tissues of the body.
   

• Vitamin E acts as an antioxidant (i.e., an inhibitor of oxidation processes) in body tissues. It protects unsaturated fats in the body from oxidation by peroxides and other free radicals.  It also acts as an protection of polyunsaturated fatty acids, cell membranes.
• The vitamin is used commercially as an antioxidant to retard the rancidification of fats, especially vegetable oils.
• Vitamin E aids in the transmission of electrical signals between nerve cells (neurons) of the brain and body.
• Vitamin E is integral to eye health, aiding in the self-repair of the retina, cornea, and uvea (the pigmented portion of the eye).
• Vitamin E can aid in scar healing by hydrating the skin, inhibiting collagen production, and reducing inflammation that can lead to tissue damage.
   

Vitamin E supplements rarely cause any harm if taken at the recommended daily dose.
But sometimes lower doses can trigger side effects like

•  nausea,
•  vomiting,
•  stomach pain,
•  diarrhea.
•  Slow down blood clotting

• Vitamin E deficiency is considered rare in the developed world, except in premature babies with low birth weight or in people with rare genetic disorders such as abetalipoproteinemia or ataxia with vitamin E deficiency.
• VitaminE can neither treat nor prevent liver disease but may help slow its progression.
• VitaminE can slow blood clotting and may need to be avoided in people taking blood thinners like Coumadin (warfarin) or Plavix (clopidogrel).
• VitaminE supplements should also be avoided in people with a history of heart attacks, stroke, bleeding disorders, or head and neck cancers.
• VitaminE supplements are presumed to be safe during pregnancy and breastfeeding.

Selenium is effective for preventing selenium deficiency.

Selenium might also help improve mood, general feelings of well-being, and quality of life in people with this condition.

Adding salt enriched with selenium to food can prevent Kashin-Beck disease in children.

Pregnant women with low levels of selenium in the blood might have a higher chance of developing pre-eclampsia.

Selenium is a mineral found in soil, water, and some foods. It is important for making many body processes work correctly.

High dosage of selenium dioxide may cause

• Muscle tenderness
• Tremor
• Lightheadedness
• Facial flushing
• Nausea
• Vomiting
• Loss of energy
• Nail changes
• Hair loss
• Irritability
• Garlic breath odor
• A metallic taste

Selenium is unsafe when taken by mouth in high doses or for a long time. 

Selenium is safe during pregnancy and breast-feeding when used short-term in amounts

Selenium is safe for children when taken by mouth appropriately.

selenium might make autoimmune disease worse by stimulating the activity of the disease. 

Blood levels of selenium can be low in people undergoing hemodialysis.

Taking selenium can worsen hypothyroidism especially in people with iodine deficiency.

Selenium might decrease the ability of sperm to move, which could reduce fertility.

Long-term use of selenium supplements might slightly increase the risk of skin cancer recurrence, but this is controversial.

Selenium might increase the risk of bleeding during and after surgery.

• Magnesium citrate is an osmotic laxative which comes in a liquid form. It is a combination of the element magnesium that is bound to citric acid.
• Magnesium citrate belongs to group of drugs known as saline laxatives, which work by pulling more water into the colon in order to help the colon empty its contents.

• Magnesium Citrate is used for the treatment of constipation.
• It may be used to treat occasional constipation, acid indigestion, or in prescribed amounts, it is used to help clear the large intestine of stool before a test (such as for a colonoscopy), procedure, or operation on the digestive system.

•  Stomach and intestinal issues like gas, diarrhea, nausea, vomiting, andstomach cramping
•  High levels of magnesium in your bloodstream
•  Imbalance in your electrolytes, or levels of minerals and compounds likesodium, potassium, calcium, chloride, and phosphate in your blood

•  If you are allergic to magnesium citrate or any of its inactive ingredients, you should not take magnesium citrate.
•  You should not take magnesium citrate if you are on a low-sodium or restricted-sodium diet.
•  If you suffer from chronic or long-term constipation, you should not take magnesium citrate - it's not safe for daily, long-term, or   frequent treatment of constipation.
• Take it atleast 2 hours after taking other medicines, as it may interfere with the absorption of other medicines.

• Silymarin is an active principle obtained from milk thistle seed (Silybummarianum). It also seems to have antioxidant and anti-inflammatory effects.
• Silymarin works by increasing the process of alcohol elimination from blood and tissues. This provides faster recovery from alcohol intoxication and as a result protects the liver from damage against harmful chemicals known as free radicals. Thereby, it helps to improve overall health of the liver.

Silymarin is a hepatoprotective agent which is used as a supportive treatment in liver diseases such as cirrhosis, hepatitis, alcoholic liver damage, drug-induced liver damage, etc

• Rash
• Dizziness
• Diarrhea
• Nausea or Vomiting
• Excessive gas in stomach
• Indigestion
• Difficulty in breathing

• Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects such as dizziness, difficulty in concentration, impaired judgment, etc. 
• This medicine is not recommended for use in pregnant or breastfeeding women unless necessary. 
• This medicine is not recommended for use in patients less than 12 years of age since the safety and efficacy of use are not clinically established.