Vitamin B1 is found in many foods including yeast, cereal grains, beans, nuts, and
meat. It is often used in combination with other B vitamins, and found in many
vitamin B complex products.

It is used for the treatment and prevention of vitamin B1 deficiency. It is also used to
treat Beriberi and Wernicke's encephalopathy.

 Allergic reaction
 Skin irritation
 Cough
 Decreased blood pressure
 Difficulty in swallowing
 Breathlessness
 Facial swelling
 Increased sweating

Vitamin B1 is LIKELY SAFE for pregnant or breast-feeding women if taken in proper
quantity.
Alcoholics and people with cirrhosis often have low levels of Vitamin B1. Nerve pain
in alcoholism can be worsened by Vitamin B1 deficiency. These people might
require Vitamin B1 supplements.
People undergoing hemodialysis treatments might have low levels of Vitamin B1. 
People with heart failure might have low levels of Vitamin B1. 
People that are critically ill such as those that had surgery might have low levels of
Vitamin B1.

Calcium Pantothenate is used in a combination with other vitamins to treat vitamin deficiency conditions.

It may also be used in a combination with other vitamins to lower the levels of lipids and cholesterol in the body.

Calcium Pantothenate is the calcium salt of pantothenic acid.

Major & minor side effects for Calcium Pantothenate

• Severe skin rash and hives
• Blistering and peeling of skin
• Difficulty in breathing
• Difficulty in swallowing
• Hoarseness of voice
• Nausea or vomiting
• Diarrhea

This supplement is considered safe for consumption by pregnant and breastfeeding women within the recommended dietary allowance.

Calcium Pantothenate may interact with many other supplements and may cause severe adverse effects. 

This supplement may be prescribed alone or in a combination with other medicines/supplements for a host of other conditions. 

This supplement should be used with caution in patients with an active disorder of the blood like anemia, thrombocytopenia, blood clotting disorders, etc.

This supplement should be used with caution in patients with a history of any gastrointestinal disorders due to the increased risk of severe adverse effects.

It is recommended to first make a dietary modification to treat the deficiency of pantothenic acid.

Biotin is a B complex vitamin used as a nutritional supplementation for dietary shortage or imbalance which may cause hair loss or total alopecia, brittle nails, skin rash in infants, and mild depression.

Biotin is a form of vitamin B that provides essential nutrients.

Major & minor side effects for Biotin

• Hypersensitivity
• Stomach discomfort and pain
• Skin rash

This medicine is considered safe for consumption by pregnant and breastfeeding women.

Use of this medicine in children should be done only under your doctor's supervision.

The effect of therapy with Biotin may occur 3 to 6 months after starting the therapy.

Dialysis patients may require a higher dose due to drug removal during dialysis.

• Methylcobalamin/Mecobalamin is a form of vitamin B12 that restores its level in the body thereby helping in treating certain anaemias and nerve problems.
• It is required for the integrity of myelin, neuronal function, proper red blood cell formation and DNA synthesis

• It is used to treat Vitamin B12 deficiency in people with Pernicious Anemia.
• It is a beneficial drug to most of the common disorders like cardiovascular disorders, diabetes, anaemia, hyperhomocysteinemia and degenerative disorders.
• Methylcobalamin helps in the synthesis of neuronal lipids, regeneration of axonal nerves and has neuroprotective activity, which promotes neurons to function properly and thus improves Alzheimer disease, Parkinsonism, Dementia and neuropathic syndromes.
• It is an approved treatment for peripheral neuropathy.
• It also helps in balancing the levels of homocysteine, which is produced in excess can cause inflammation of blood vessels.

• Nausea and vomiting
• Diarrhoea
• Decreased appetite
• Dizziness
• Headache
• Skin rash
• Chest pain and discomfort

• Methylcobalamin can show some serious side effects in patients who might suffer from other conditions.
• Everyone needs to consume this medicine only after clinical consultation. The serious side effects of Methylcobalamin can include the formation of clots in limbs, depleted levels of potassium in the blood, a buildup of fluid in the lungs, heart failure and in some cases, anaphylactic reactions such as swollen tongue and throat, and hives.
• Consuming Methylcobalamin is not advisable for patients suffering from optic atrophy, which is a nerve condition that affects the eye.
• People who are suffering from infections or patients who have a low iron level in their body should be careful before taking Methylcobalamin and should only do so after the consultation of the doctor.
• It is not advised for mothers to consume Methylcobalamin if they are breastfeeding. Mother’s milk is a rich source of Vitamin B12 and consuming additional supplements while breastfeeding can have adverse effects on the baby.

• Folic acid is the synthetic form of folate, which is a naturally occurring B vitamin. Folate helps make DNA and other genetic material. It is especially important in prenatal health.
• Folate, also called vitamin B-9, is a B vitamin that naturally occurs in certain foods. Folic acid is the form of folate that manufacturers add to vitamin supplements and fortified foods.

• It helps the body make healthy new red blood cells.
• In its deficiency a person can develop anemia, leading to fatigue, weakness, and a pale complexion.
• It leads to folate deficiency anemia.
• Folate is also important for the synthesis and repair of DNA and other genetic material.
• It is particularly important to get during pregnancy. Folate deficiency during pregnancy can lead to neural tube irregularities, such as spina bifida and anencephaly.
• Folic acid is crucial for early fetal development.
• Neural tube irregularities - Taking folic acid supplements before and during pregnancy will help prevent neural tube irregularities in the fetus.
• It may also reduce the risks of preterm birth, heart irregularities, and cleft palate, among other things.
• Depression - Taking folic acid supplements could make depression medications more effective.
• The Office on Women’s Health recommend that women who are or might become pregnant take 400–800 mcg of folic acid per day, and that people with spina bifida or a family history of neural tube irregularities take 4,000 mcg per day. Those who are breastfeeding should aim to take around 500 mcg per day.
• The body absorbs folic acid from supplements and fortified foods better than the folate from naturally occurring foods.

Skin reactions, seizures, gases problem, diarrhea, irritability, confusion, stomach upset, loss of appetite, and hypersensitivity

It is important to note that folic acid can interact with certain medications.

A person should speak to a doctor before taking folic acid if they have any of the following:

• Epilepsy
• Type 2 diabetes
• Rheumatoid arthritis
• Lupus
• Inflammatory bowel disease (ibd)
• Celiac disease

People undergoing kidney dialysis may also wish to avoid taking folic acid.

Ferrous Ascorbate is used for the treatment and prevention of iron deficiency anemia when the amount of iron taken in from the diet is not sufficient. It is also be used to treat anemia associated with chronic kidney failure. This medicine is used only to treat hemoglobin abnormalities due to iron deficiency.

• Iron Deficiency Anemia -This medicine is used for the treatment and prevention of iron deficiency anemia. It is also be used to treat iron deficiency anemia associated with chronic kidney failure. 

When not to use?

• Allergy
• Iron overload

Anaphylactic reactions, constipation, joint pains, chest pain, pigmentation of skin, difficulty in breathing, cardiac chest pain, diarrhea, Headache, fever.

• This medicine is not recommended for use in pregnant women unless necessary. However, your doctor may prescribe this medicine if the benefits significantly outweigh the risks. The risks and benefits should be discussed with the doctor before taking this medicine.
• This medicine is not recommended for use in breastfeeding women unless necessary.
• Accidental ingestion of this medicine may lead to fatal iron poisoning in children below 6 years of age. Seek emergency medical treatment in case of a suspected overdose.
• Gastrointestinal disorders - This medicine should be used with caution in patients with gastrointestinal irritation or conditions such as peptic ulcer disease, enteritis, ulcerative colitis, etc. due to the risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
• Use in elderly population - This medicine should be used with extreme caution in elderly patients due to the risk of adverse effects. Close monitoring of the clinical condition, appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.