• Selenium is used in the treatment of natural deficiency.
• Selenium is essential for the conversion of thyroxine (T4) to the biologically active thyroid hormone triiodothyronine (T3) thereby it is important in thyroid hormone functioning.
• Selelium is not produced in the body but is needed for the proper immune system and thyroid function.
• It is found in soil, water and some food.

• Selelium is a powerful mineral. It plays a key role in metabolism and the functioning of the Thyroid glands.
• Selenium has antioxidant properties.
• Selenium is used to cure Prostate cancer.
• Some of the diseases due to deficiency of selelium are HIV, Crohn’s disease.
• It is also used to treat diseases like Asthma, Arthritis, Dandruff and Infertility.

• Selenium deficiency produces biochemical changes that might predispose people who experience additional stresses to develop certain illnesses.
• Side effects may include fingernail loss, skin rash, fatigue, irritability and weight loss.

It is observed that overdose of Selelium may increase the chances of non- melanoma (Skin cancer).

Lycopene is a powerful antioxidant that may help protect cells from damage. Hence, it is used for high blood pressure, high cholesterol, cancer, and many other conditions.

Used to treat prostate cancer, leukoplakia, asthma and heart disease.

Discoloration of the skin - Lycopenemia

•  Avoid if pregnant
•  It might increase the risk of bleeding during and after surgery. Stop using lycopene supplements at least 2 weeks before a scheduled surgery.
•  Those taking medication for low blood pressure should not take lycopene.

• Iodine is a chemical element. The body needs iodine but cannot make it. The iodine needed by the body must come from the diet. Iodine helps convert thyroid stimulating hormone (TSH) to triiodothyronine (T3) and thyroxine (T4). This conversion is important for the thyroid to function properly.
• An iodine imbalance can lead to an overactive or underactive thyroid.

• The thyroid gland needs iodine to make hormones. Lack of iodine can cause an enlarged thyroid gland (goiter), which causes a swollen neck.
• It is also used for treating lumpy breasts (fibrocystic breast disease) and breast pain (mastalgia).
• Iodine deficiency and the resulting low levels of thyroid hormone can cause women to stop ovulating, leading to infertility. Iodine deficiency can also lead to an autoimmune disease of the thyroid and may increase the risk of getting thyroid cancer.
• Iodine is also used for radiation emergencies, to protect the thyroid gland against radioactive iodides.
• Iodine is sometimes applied to the skin for skininflammation and to kill germs and facilitate wound healing.
• It is also used prevent soreness inside the mouth or along the digestive tract, and other conditions, but there is no good scientific evidence to support these uses.
• Iodine is used in the vagina to prevent post-Cesarean swelling of the lining of the uterus. Iodine is also used for water purification.

•  burning mouth/throat, sore teeth/gums, swelling inside the mouth, increased saliva,
•  eye irritation/swollen eyelids,
•  severe headache,
•  swelling of the front of the neck/throat (goiter),
•  signs of decreased thyroid gland function (e.g., weight gain, cold intolerance, slow/irregular heartbeat, constipation, unusual tiredness), confusion,
•  numbness/tingling/pain/weakness of the hands/feet.

Excessive iodine may cause hypothyroidism by feedback inhibition of thyroid hormone production and conversion of triiodothyronine(T3) to less active thyroxine(T4). Use caution in patients with renal impairment. Iodine enters breast milk; use caution if breastfeeding