• Methylcobalamin/Mecobalamin is a form of vitamin B12 that restores its level in the body thereby helping in treating certain anaemias and nerve problems.
• It is required for the integrity of myelin, neuronal function, proper red blood cell formation and DNA synthesis

• It is used to treat Vitamin B12 deficiency in people with Pernicious Anemia.
• It is a beneficial drug to most of the common disorders like cardiovascular disorders, diabetes, anaemia, hyperhomocysteinemia and degenerative disorders.
• Methylcobalamin helps in the synthesis of neuronal lipids, regeneration of axonal nerves and has neuroprotective activity, which promotes neurons to function properly and thus improves Alzheimer disease, Parkinsonism, Dementia and neuropathic syndromes.
• It is an approved treatment for peripheral neuropathy.
• It also helps in balancing the levels of homocysteine, which is produced in excess can cause inflammation of blood vessels.

• Nausea and vomiting
• Diarrhoea
• Decreased appetite
• Dizziness
• Headache
• Skin rash
• Chest pain and discomfort

• Methylcobalamin can show some serious side effects in patients who might suffer from other conditions.
• Everyone needs to consume this medicine only after clinical consultation. The serious side effects of Methylcobalamin can include the formation of clots in limbs, depleted levels of potassium in the blood, a buildup of fluid in the lungs, heart failure and in some cases, anaphylactic reactions such as swollen tongue and throat, and hives.
• Consuming Methylcobalamin is not advisable for patients suffering from optic atrophy, which is a nerve condition that affects the eye.
• People who are suffering from infections or patients who have a low iron level in their body should be careful before taking Methylcobalamin and should only do so after the consultation of the doctor.
• It is not advised for mothers to consume Methylcobalamin if they are breastfeeding. Mother’s milk is a rich source of Vitamin B12 and consuming additional supplements while breastfeeding can have adverse effects on the baby.

Lycopene is a powerful antioxidant that may help protect cells from damage. Hence, it is used for high blood pressure, high cholesterol, cancer, and many other conditions.

Used to treat prostate cancer, leukoplakia, asthma and heart disease.

Discoloration of the skin - Lycopenemia

•  Avoid if pregnant
•  It might increase the risk of bleeding during and after surgery. Stop using lycopene supplements at least 2 weeks before a scheduled surgery.
•  Those taking medication for low blood pressure should not take lycopene.

• Vitamin A is vital for a healthy immune system, bone growth, vision, cell recognition and reproduction. Vitamin A often works as an antioxidant, fighting cell damage, but it also has many other uses. It has a vital role in the formation of heart, lungs, and kidney.
• Other functions of vitamin A include the formation and maintenance of teeth, bones, soft tissue, white blood cells, the immune system and mucus membranes. 
• Most people get enough vitamin A from their diets. However, a doctor might suggest vitamin A supplements to people who have vitamin A deficiencies. People most likely to have vitamin A deficiency are those with diseases (such as digestive disorders) or very poor diets.

• Vitamin A is used for improving the eyesight, maintaining cells of the skin and the lining of the digestive, urinary and respiratory tracts.
• It also helps in the formation of red and white blood cells in our body that are important to carry out the various essential functions of our body.
• Topical and oral retinoids are common prescription treatments for acne and other skin conditions, including wrinkles. 
• Oral vitamin A is also used as a treatment for measles and dry eye in people with low levels of vitamin A. 
• Vitamin A is also used for a specific type of leukemia.
• Vitamin A has been studied as a treatment for many other conditions, including cancers, cataracts, and HIV. However, the results are inconclusive.

• Night blindness
• A higher risk of infections, especially in the throat, chest, and abdomen
• Follicular hyperkeratosis, leading to dry, bumpy skin.
• Fertility issues
• Delayed growth in children
• Symptoms of vitamin A toxicity include dry skin, joint pain, vomiting, headaches, confusion.

• If you take too much of Vitamin A, it can lead to birth defects, abnormalities of the liver and disorders of the central nervous system.
• It can also decrease bone mineral density, leading to an increased risk of osteoporosis.
• This is because an excess of Vitamin A suppresses the building up of bones and increases its breakdown.
• The rate of calcium absorption by Vitamin D can also get affected due to excess of Vitamin A. Therefore, it is advised to use Vitamin A only as directed by your doctor.
• Interactions. Vitamin A supplements may interact with some birth control pills, blood thinners (Coumadin), acne medicines (isotretinoin), cancer treatments, and many other drugs.
• People who drink heavily or have kidney or liver disease shouldn’t take vitamin A supplements without talking to a doctor.

Vitamin B1 is found in many foods including yeast, cereal grains, beans, nuts, and
meat. It is often used in combination with other B vitamins, and found in many
vitamin B complex products.

It is used for the treatment and prevention of vitamin B1 deficiency. It is also used to
treat Beriberi and Wernicke's encephalopathy.

 Allergic reaction
 Skin irritation
 Cough
 Decreased blood pressure
 Difficulty in swallowing
 Breathlessness
 Facial swelling
 Increased sweating

Vitamin B1 is LIKELY SAFE for pregnant or breast-feeding women if taken in proper
quantity.
Alcoholics and people with cirrhosis often have low levels of Vitamin B1. Nerve pain
in alcoholism can be worsened by Vitamin B1 deficiency. These people might
require Vitamin B1 supplements.
People undergoing hemodialysis treatments might have low levels of Vitamin B1. 
People with heart failure might have low levels of Vitamin B1. 
People that are critically ill such as those that had surgery might have low levels of
Vitamin B1.

Vitamin B6 is a water-soluble vitamin. Water-soluble vitamins dissolve in water so the body cannot store them.Vitamin B6 is a group of related compounds. It is necessary for maintaining important functions in the body such as glucose and amino acid metabolism, production of RBCs, proper functioning of the nervous system, etc

• Vitamin B6 is used to treat or prevent vitamin B6 deficiency.
• It is also used to treat a certain type of anemia (lack of red blood cells).
• This medicine injection is also used to treat some types of seizure in babies.
• Vitamin B6 (Pyridoxine) provides essential nutrients.
• Vitamin B6 helps the body to:
• Make antibodies. Antibodies are needed to fight many diseases.
• Maintain normal nerve function.
• Make hemoglobin. Hemoglobin carries oxygen in the red blood cells to the tissues. A vitamin B6 deficiency can cause a form of anemia.
• Break down proteins. The more protein you eat, the more vitamin B6 you need.
• Keep blood sugar (glucose) in normal ranges.
• Vitamin B6 is being studied in the prevention of hand-foot syndrome

• Clumsiness
• Numbness of hands or feet
• Unsteady walk
• Sleepiness

• Follow your doctor's instructions about any restrictions on food, beverages, or activity.
• Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
• This medicine is not recommended for use in breastfeeding women unless necessary.

• Selenium is used in the treatment of natural deficiency.
• Selenium is essential for the conversion of thyroxine (T4) to the biologically active thyroid hormone triiodothyronine (T3) thereby it is important in thyroid hormone functioning.
• Selelium is not produced in the body but is needed for the proper immune system and thyroid function.
• It is found in soil, water and some food.

• Selelium is a powerful mineral. It plays a key role in metabolism and the functioning of the Thyroid glands.
• Selenium has antioxidant properties.
• Selenium is used to cure Prostate cancer.
• Some of the diseases due to deficiency of selelium are HIV, Crohn’s disease.
• It is also used to treat diseases like Asthma, Arthritis, Dandruff and Infertility.

• Selenium deficiency produces biochemical changes that might predispose people who experience additional stresses to develop certain illnesses.
• Side effects may include fingernail loss, skin rash, fatigue, irritability and weight loss.

It is observed that overdose of Selelium may increase the chances of non- melanoma (Skin cancer).

Lysine is an amino acid that acts as a building block for the protein in your body. This amino acid is essential since your body cannot produce it on its own.

• Our body’s need lysine to provide healthy functioning. Since lysine helps your body absorb calcium, it helps you treat anxiety.
• It plays a vital role in fighting diseases. Lysine helps the body produce infection-fighting antibodies, enzymes, hormones, and body tissues.
• Lysine supplements are sometimes used to treat a wide range of conditions, including Canker sores, Diabetes, High triglyceride levels, improved muscle strength and athletic performance, Bedsores, Schizophrenia.

• Diarrhoea
• Abdominal Pain
• Chronic Kidney (Renal) Failure
• Inflammation in the Kidney (Interstitial Nephritis)
• Increased Calcium Absorption

• Lysine supplements are possibly safe for most people when taken by mouth in appropriate doses for up to one year or when applied to the skin for up to one year.
• Certain people should avoid the supplement.
• There is not enough evidence to know if it is safe for women who are pregnant or breastfeeding.
• Also, those with kidney disease, intolerance to lysinuric protein, or osteoporosis should speak to their healthcare provider when taking the supplement.