Coenzyme Q10 is most commonly used for conditions that affect the heart such as heart failure and fluid build up in the body, chest pain, and high blood pressure. It is also used for preventing migraine headache, Parkinson disease, and many other conditions.

Coenzyme Q10 is a vitamin-like substance found throughout the body, but especially in the heart, liver, kidney, and pancreas.

Major &Minor side effects of Coenzyme Q10

• Stomach upset
• Nausea
• Loss of appetite
• Vomiting
• Diarrhea
• Allergic skin rashes
• Low blood pressure

This medicine is safe when taken by mouth appropriately during pregnancy.

This medicine is safe to be taken by children under medical supervision.

People undergoing chemotherapy with a class of drugs called alkylating agents should use coenzyme Q10 with caution.

Coenzyme Q10 might lower blood pressure.

Cigarette smoking depletes the amount of coenzyme Q10 stored by the body.

Coenzyme Q10 might interfere with blood pressure control during and after surgery.

DHA is used as a supplement for premature babies and as an ingredient in baby formula during the first year of life to promote better mental development. It is also used in infant formula to prevent lung diseases, allergic diseases such as eczema or hay fever, and diarrhea.

In some cases, DHA is used in combination with arachidonic acid.

DHA is also taken by mouth alone or along with EPA to improve mental function in healthy people or those with mental impairment.

It is also used to improve mental function in people with dementia or age-related mental decline.

 It is also taken by mouth for attention deficit-hyperactivity disorder (ADHD), depression, aggressive behavior, Alzheimer's disease, autism, and to prevent relapse in schizophrenic patients who stop taking antipsychotic medication.

Docosahexaenoic acid (DHA) belongs to the class of medications called as nutritional supplements. DHA plays a vital role in the brain development. DHA decreases cholesterol and triglyceride levels, inhibits platelet aggregation and oxidation of LDL, decreases the synthesis of inflammatory markers such as prostaglandins. Overall, DHA plays a vital role in reducing the heart and circulatory disease risks.

Major & minor side effects for Docosahexaenoic acid

• Bad breath
• Heartburn
• Nausea
• Weight gain
• Allergy

Seek immediate medical attention if you experience any allergic symptoms.

Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding.

Do not take if allergic to DHA or any of its ingredients.

Do not take if having problem with aspirin-sensitivity and hypertension.

Do not take if allergic to fish products.

Lycopene being an antioxidant, may stop cancer growth and build up enzymes in the body that help break down cancer-causing agents.as well as its use in the prevention of cardiovascular disease.

Lycopene may help prevent strokes, particularly strokes caused by blood clots.

Lycopene along with other carotenoids may also protect against UV damage caused by the sun.

Lycopene is a natural compound that is found in bright red fruits and vegetables like tomatoes, watermelon, and grapefruit.

Lycopene acts an antioxidant by fighting free radicals in the body. Due to its antioxidant property, it reduces the risk of cancer and cardiovascular disease.

Major & minor side effects for Lycopene prepn

• Nausea
• Diarrhea
• Indigestion
• Vomiting

This medicine is not recommended for use in pregnant and breastfeeding women unless absolutely necessary.

Lycopene may also increase the risk of bleeding when taking certain medications.

Certain supplements like beta-carotene, calcium, and lutein, when taken together with lycopene, may decrease the amount of lycopene absorbed by the gut. 

Chronic, excessive alcohol consumption may also cause a side effect with lycopene.

The primary ingredient of L-Arginine is L-arginine, which is an amino acid present in the body. L-arginine plays an important role in many vital functions in the human body. 

 

L-arginine is a nonessential amino acid that may play an important role in the treatment of heart disease due to its block arterial plaque buildup, blood clots, platelet clumping, and to increase blood flow through the coronary artery. L- arginine is commonly sold as a health supplement claiming to improve vascular health and treat erectile dysfunction in men. L-arginine, which is promoted as a human growth stimulant, has also been used in bodybuilding

•  Abdominal pain
•  Difficulty in breathing
•  Allergic skin reaction
•  Low blood pressure
•  Low blood sugar levels
•  Diarrhea
•  Worsening of asthma
•  Bloating
•  Gout

• This supplement should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. 
• Regular monitoring of kidney function tests is necessary while receiving this supplement.
• This supplement is not recommended for use in patients who have recently undergone a surgery or are scheduled to undergo surgery in the near future due to the increased risk of alterations in the blood pressure levels. It is advised that you stop the use of this supplement at least 2 weeks prior to a scheduled surgery.
• This supplement is not recommended for use in patients suffering from a herpes infection due to the increased risk of worsening of the patient’s condition.

Selenium is effective for preventing selenium deficiency.

Selenium might also help improve mood, general feelings of well-being, and quality of life in people with this condition.

Adding salt enriched with selenium to food can prevent Kashin-Beck disease in children.

Pregnant women with low levels of selenium in the blood might have a higher chance of developing pre-eclampsia.

Selenium is a mineral found in soil, water, and some foods. It is important for making many body processes work correctly.

High dosage of selenium dioxide may cause

• Muscle tenderness
• Tremor
• Lightheadedness
• Facial flushing
• Nausea
• Vomiting
• Loss of energy
• Nail changes
• Hair loss
• Irritability
• Garlic breath odor
• A metallic taste

Selenium is unsafe when taken by mouth in high doses or for a long time. 

Selenium is safe during pregnancy and breast-feeding when used short-term in amounts

Selenium is safe for children when taken by mouth appropriately.

selenium might make autoimmune disease worse by stimulating the activity of the disease. 

Blood levels of selenium can be low in people undergoing hemodialysis.

Taking selenium can worsen hypothyroidism especially in people with iodine deficiency.

Selenium might decrease the ability of sperm to move, which could reduce fertility.

Long-term use of selenium supplements might slightly increase the risk of skin cancer recurrence, but this is controversial.

Selenium might increase the risk of bleeding during and after surgery.

Vitamin B1 is found in many foods including yeast, cereal grains, beans, nuts, and
meat. It is often used in combination with other B vitamins, and found in many
vitamin B complex products.

It is used for the treatment and prevention of vitamin B1 deficiency. It is also used to
treat Beriberi and Wernicke's encephalopathy.

 Allergic reaction
 Skin irritation
 Cough
 Decreased blood pressure
 Difficulty in swallowing
 Breathlessness
 Facial swelling
 Increased sweating

Vitamin B1 is LIKELY SAFE for pregnant or breast-feeding women if taken in proper
quantity.
Alcoholics and people with cirrhosis often have low levels of Vitamin B1. Nerve pain
in alcoholism can be worsened by Vitamin B1 deficiency. These people might
require Vitamin B1 supplements.
People undergoing hemodialysis treatments might have low levels of Vitamin B1. 
People with heart failure might have low levels of Vitamin B1. 
People that are critically ill such as those that had surgery might have low levels of
Vitamin B1.

Vitamin B12 is used in the treatment of vitamin B12 deficiency.

Vitamin B12 is a nutrient which the body requires in small amounts to make red blood cells, generate energy, and keep nerve cells healthy.

• Symptoms of Vitamin B12 Deficiency
• Weakness, tiredness, or lightheadedness
• Anemia
• Heart palpitations and shortness of breath
• Pale skin
• A smooth tongue
• Constipation, diarrhea, loss of appetite, or gas 
• Nerve problems like numbness or tingling, muscle weakness, and problems walking
• Vision loss
• Mental problems like depression, memory loss, or behavioral changes 

• Most people can prevent vitamin B12 deficiency by eating enough meat, poultry, seafood, dairy products, and eggs.
• If you don't eat animal products, or you have a medical condition that limits how well your body absorbs nutrients, you can take vitamin B12 in a multivitamin or other supplement and foods fortified with vitamin B12.

Vitamin B6 is a water-soluble vitamin. Water-soluble vitamins dissolve in water so the body cannot store them.Vitamin B6 is a group of related compounds. It is necessary for maintaining important functions in the body such as glucose and amino acid metabolism, production of RBCs, proper functioning of the nervous system, etc

• Vitamin B6 is used to treat or prevent vitamin B6 deficiency.
• It is also used to treat a certain type of anemia (lack of red blood cells).
• This medicine injection is also used to treat some types of seizure in babies.
• Vitamin B6 (Pyridoxine) provides essential nutrients.
• Vitamin B6 helps the body to:
• Make antibodies. Antibodies are needed to fight many diseases.
• Maintain normal nerve function.
• Make hemoglobin. Hemoglobin carries oxygen in the red blood cells to the tissues. A vitamin B6 deficiency can cause a form of anemia.
• Break down proteins. The more protein you eat, the more vitamin B6 you need.
• Keep blood sugar (glucose) in normal ranges.
• Vitamin B6 is being studied in the prevention of hand-foot syndrome

• Clumsiness
• Numbness of hands or feet
• Unsteady walk
• Sleepiness

• Follow your doctor's instructions about any restrictions on food, beverages, or activity.
• Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
• This medicine is not recommended for use in breastfeeding women unless necessary.

• Vitamin E is essential to the normal functioning of the human body. It plays a central role in your immune system and functions as an antioxidant, neutralizing free radicals that damage cells at the genetic level.
• Vitamin E is fat-soluble, meaning that it is dissolved in fat and able to be stored in the liver and fatty tissues of the body.
   

• Vitamin E acts as an antioxidant (i.e., an inhibitor of oxidation processes) in body tissues. It protects unsaturated fats in the body from oxidation by peroxides and other free radicals.  It also acts as an protection of polyunsaturated fatty acids, cell membranes.
• The vitamin is used commercially as an antioxidant to retard the rancidification of fats, especially vegetable oils.
• Vitamin E aids in the transmission of electrical signals between nerve cells (neurons) of the brain and body.
• Vitamin E is integral to eye health, aiding in the self-repair of the retina, cornea, and uvea (the pigmented portion of the eye).
• Vitamin E can aid in scar healing by hydrating the skin, inhibiting collagen production, and reducing inflammation that can lead to tissue damage.
   

Vitamin E supplements rarely cause any harm if taken at the recommended daily dose.
But sometimes lower doses can trigger side effects like

•  nausea,
•  vomiting,
•  stomach pain,
•  diarrhea.
•  Slow down blood clotting

• Vitamin E deficiency is considered rare in the developed world, except in premature babies with low birth weight or in people with rare genetic disorders such as abetalipoproteinemia or ataxia with vitamin E deficiency.
• VitaminE can neither treat nor prevent liver disease but may help slow its progression.
• VitaminE can slow blood clotting and may need to be avoided in people taking blood thinners like Coumadin (warfarin) or Plavix (clopidogrel).
• VitaminE supplements should also be avoided in people with a history of heart attacks, stroke, bleeding disorders, or head and neck cancers.
• VitaminE supplements are presumed to be safe during pregnancy and breastfeeding.