Rifampicin is an antibiotic. It works by inactivating a bacterial enzyme (RNA- polymerase) which is required by bacteria to make essential proteins and to reproduce. It should be taken with other medicines to prevent the spread of infection.
 

• It's approved to treat all forms of tuberculosis (TB) caused by Mycobacterium tuberculosis, including latent TB infections.
• Rifampin is also used to eliminate meningitis-causing Neisseria meningitidis from the nose and throat of people who don't have symptoms so they don't spread theinfection to others.
• Rifampicin is also used for leprosy.

•  Abdominal pain
•  Dizziness
•  Headache
•  Yellow colored eyes or skin
•  Nausea and Vomiting
•  Skin rash
•  Loss of appetite
•  Unusual behavior
•  Muscle pain
•  Weakness

•  It is best taken on an empty stomach. If you get an upset stomach, try taking it with small portions of food. 
•  This medicine may cause reddish colouration of the urine, sweat, sputum and tears. Avoid using contact lenses since they may become discolored.
•  Avoid taking hormone-based birth control methods as Rifampicin may decrease their effectiveness.
•  Tell your doctor immediately if you experience unusual tiredness or loss of appetite, fever or chills.