R CINEX 450MG is a fixed dose combination of Rifampicin and Isoniazid, two powerful antibiotics commonly used in the treatment of tuberculosis (TB). Rifampicin is an antimycobacterial agent that works by inhibiting the growth of TB bacteria, while Isoniazid is a bactericidal agent that kills the TB bacteria. This combination provides an effective treatment for TB infections, reducing the bacterial load and preventing the development of drug resistance. It is essential to complete the full course of treatment as prescribed by your healthcare provider to ensure successful eradication of the TB bacteria.

• Treatment of tuberculosis (TB) infections
• Prevention of active TB in individuals exposed to the disease

• Vomiting
• Nausea
• Loss of appetite
• Abdominal pain
• Liver toxicity
• Skin rash

Take R CINEX 450MG orally, as instructed by your doctor. It is usually recommended to take the medicine on an empty stomach, at least an hour before or two hours after meals. Do not crush or chew the capsules; swallow them whole with a glass of water.

• Pregnancy - R CINEX 450MG should be used with caution during pregnancy. It is essential to consult your doctor before taking this medicine, as the benefits and risks need to be carefully evaluated.
• Alcohol - It is advisable to avoid alcohol while taking R CINEX 450MG , as it may increase the risk of liver toxicity and interfere with the effectiveness of the medication.
• Old Age - No specific precautions need to be taken while using R CINEX 450MG in older adults.
• Breast Feeding - R CINEX 450MG should not be used while breastfeeding unless recommended by your doctor. It is important to discuss the potential risks and benefits with your healthcare provider.
• Children - Special caution should be exercised when administering R CINEX 450MG to children. The dose may need to be adjusted based on the child's weight and age. Consult your pediatrician for the appropriate dosage and duration of treatment.

• Store R CINEX 450MG in a cool and dry place. -
• Keep it away from direct heat and sunlight. -
• Keep out of the reach of children. -

• Drug-Drug - Inform your doctor about all the medicines you are currently taking, as R CINEX 450MG may interact with certain medications, including anticoagulants, antiepileptic drugs, antacids, and certain antibiotics. It is important to follow your doctor’s advice and take necessary precautions.
• Drug-Food - Avoid consuming foods or drinks rich in tyramine, such as cheese, cured meats, and fermented products, as they may interact with Rifampicin and cause a hypertensive reaction.
• Drug-Disease - Discuss your medical history and any underlying health conditions with your doctor before starting R CINEX 450MG . This is particularly important if you have liver disease, kidney disease, or a history of mental health disorders.

• Q. What should I do if I miss a dose of R CINEX 450MG ?
  If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.
• Q. Can I stop taking R CINEX 450MG if I feel better?
  No, it is crucial to complete the full course of treatment as prescribed, even if you start feeling better. Premature discontinuation of medication may lead to incomplete eradication of TB bacteria and increase the risk of drug resistance.
• Q. What are the common side effects of R CINEX 450MG ?
  Common side effects of R CINEX 450MG may include nausea, vomiting, loss of appetite, skin rash, and liver toxicity. It is important to discuss any persistent or bothersome side effects with your doctor.
• Q. Can I drink grapefruit juice while taking R CINEX 450MG ?
  It is generally advisable to avoid drinking grapefruit juice while taking R CINEX 450MG , as it can interact with Rifampicin and alter its effectiveness.
• Q. Can I take R CINEX 450MG with my other regular medications?
  Inform your doctor about all the medicines you are currently taking, including over-the-counter medications and herbal supplements, as they may interact with R CINEX 450MG . It is important to follow the advice of your healthcare provider.