• Vitamin E is essential to the normal functioning of the human body. It plays a central role in your immune system and functions as an antioxidant, neutralizing free radicals that damage cells at the genetic level.
• Vitamin E is fat-soluble, meaning that it is dissolved in fat and able to be stored in the liver and fatty tissues of the body.
   

• Vitamin E acts as an antioxidant (i.e., an inhibitor of oxidation processes) in body tissues. It protects unsaturated fats in the body from oxidation by peroxides and other free radicals.  It also acts as an protection of polyunsaturated fatty acids, cell membranes.
• The vitamin is used commercially as an antioxidant to retard the rancidification of fats, especially vegetable oils.
• Vitamin E aids in the transmission of electrical signals between nerve cells (neurons) of the brain and body.
• Vitamin E is integral to eye health, aiding in the self-repair of the retina, cornea, and uvea (the pigmented portion of the eye).
• Vitamin E can aid in scar healing by hydrating the skin, inhibiting collagen production, and reducing inflammation that can lead to tissue damage.
   

Vitamin E supplements rarely cause any harm if taken at the recommended daily dose.
But sometimes lower doses can trigger side effects like

•  nausea,
•  vomiting,
•  stomach pain,
•  diarrhea.
•  Slow down blood clotting

• Vitamin E deficiency is considered rare in the developed world, except in premature babies with low birth weight or in people with rare genetic disorders such as abetalipoproteinemia or ataxia with vitamin E deficiency.
• VitaminE can neither treat nor prevent liver disease but may help slow its progression.
• VitaminE can slow blood clotting and may need to be avoided in people taking blood thinners like Coumadin (warfarin) or Plavix (clopidogrel).
• VitaminE supplements should also be avoided in people with a history of heart attacks, stroke, bleeding disorders, or head and neck cancers.
• VitaminE supplements are presumed to be safe during pregnancy and breastfeeding.

Biotin is a B complex vitamin used as a nutritional supplementation for dietary shortage or imbalance which may cause hair loss or total alopecia, brittle nails, skin rash in infants, and mild depression.

Biotin is a form of vitamin B that provides essential nutrients.

Major & minor side effects for Biotin

• Hypersensitivity
• Stomach discomfort and pain
• Skin rash

This medicine is considered safe for consumption by pregnant and breastfeeding women.

Use of this medicine in children should be done only under your doctor's supervision.

The effect of therapy with Biotin may occur 3 to 6 months after starting the therapy.

Dialysis patients may require a higher dose due to drug removal during dialysis.

• Selenium is used in the treatment of natural deficiency.
• Selenium is essential for the conversion of thyroxine (T4) to the biologically active thyroid hormone triiodothyronine (T3) thereby it is important in thyroid hormone functioning.
• Selelium is not produced in the body but is needed for the proper immune system and thyroid function.
• It is found in soil, water and some food.

• Selelium is a powerful mineral. It plays a key role in metabolism and the functioning of the Thyroid glands.
• Selenium has antioxidant properties.
• Selenium is used to cure Prostate cancer.
• Some of the diseases due to deficiency of selelium are HIV, Crohn’s disease.
• It is also used to treat diseases like Asthma, Arthritis, Dandruff and Infertility.

• Selenium deficiency produces biochemical changes that might predispose people who experience additional stresses to develop certain illnesses.
• Side effects may include fingernail loss, skin rash, fatigue, irritability and weight loss.

It is observed that overdose of Selelium may increase the chances of non- melanoma (Skin cancer).